| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GABRP/GABA A receptor pi |
| Specificity: |
This antibody reacts specifically with GABRP/GABA A receptor pi |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GABRP/GABA A receptor pi |
| Gene ID: |
2568 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Both GABAA and GABAC are ligand-gated ion channels, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC, In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid), however, they are structurally and functionally distinct, GAD-65 and GAD-67 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GABRP/GABA A receptor pi Antibody |
| Other name: |
Anti-GABRP/GABA A receptor pi |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
GABRP/GABA A receptor pi |
| Short name: |
Fluor 594, Anti-GABRP/GABA A receptor pi |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GABRP/GABA A receptor pi |
| Identity: |
4089 |
| Gene: |
GABRP |
More about : GABRP |
| Long gene name: |
gamma-aminobutyric acid type A receptor pi subunit |
| Synonyms gene name: |
gamma-aminobutyric acid (GABA) A receptor, pi |
| Synonyms name: |
GABA(A) receptor, pi |
| Locus: |
5q35, 1 |
| Discovery year: |
1997-06-18 |
| GenBank acession: |
U95367 |
| Entrez gene record: |
2568 |
| Pubmed identfication: |
9182563 |
| RefSeq identity: |
NM_014211 |
| Classification: |
Gamma-aminobutyric acid type A receptor subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000130443 |