| Long name: |
Biotin Conjugated, GABRP/GABA A receptor pi Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABRP/GABA A receptor pi |
| Specificity: |
This is a highly specific antibody against GABRP/GABA A receptor pi |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GABRP/GABA A receptor pi |
| Gene ID number: |
2568 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both GABAA and GABAC are ligand-gated ion channels, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC, In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid), however, they are structurally and functionally distinct, GAD-65 and GAD-67 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
GABRP/GABA A receptor pi Conjugated |
| Short name: |
Conjugated, GABRP/GABA A receptor pi Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GABRP/GABA A receptor pi (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4089 |
| Gene: |
GABRP |
More about : GABRP |
| Long gene name: |
gamma-aminobutyric acid type A receptor pi subunit |
| Synonyms gene name: |
gamma-aminobutyric acid (GABA) A receptor, pi |
| Synonyms name: |
GABA(A) receptor, pi |
| Locus: |
5q35, 1 |
| Discovery year: |
1997-06-18 |
| GenBank acession: |
U95367 |
| Entrez gene record: |
2568 |
| Pubmed identfication: |
9182563 |
| RefSeq identity: |
NM_014211 |
| Classification: |
Gamma-aminobutyric acid type A receptor subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000130443 |