| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GABRA6/GABA A Receptor alpha 6 |
| Specificity: |
This antibody reacts specifically with GABRA6/GABA A Receptor alpha 6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
-2, Both GABAA and GABAC are ligand-gated ion channels, GABA T-2 and GABA T-3 (also designated GAT-1, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC, GABA transporters have also been identified and include GABA T-1, GABAA R beta 1-3, GABAA R delta, GABAA R gamma , GABAA R gamma 1-3, In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing, Members of the GABAA receptor family include GABAA R alpha 1-6, The GABA transporters function to terminate GABA action, The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta, and -3), function to catalyze the production of GABA (gamma-aminobutyric acid), glutamate decarboxylases, however, they are structurally and functionally distinct, GAD-65 and GAD-67 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GABRA6/GABA A Receptor alpha 6 Antibody |
| Other name: |
Anti-GABRA6/GABA A Receptor alpha 6 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GABRA6/GABA A Receptor alpha 6 |
| Short name: |
Fluor 594, Anti-GABRA6/GABA A Receptor alpha 6 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GABRA6/GABA A Receptor a 6 |
| Identity: |
4080 |
| Gene: |
GABRA6 |
More about : GABRA6 |
| Long gene name: |
gamma-aminobutyric acid type A receptor alpha6 subunit |
| Synonyms gene name: |
alpha 6 , gamma-aminobutyric acid (GABA) A receptor |
| Synonyms name: |
GABA(A) receptor, alpha 6 |
| Locus: |
5q34 |
| Discovery year: |
1994-04-20 |
| Entrez gene record: |
2559 |
| Pubmed identfication: |
8020978 |
| Classification: |
Gamma-aminobutyric acid type A receptor subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000130351 |