| Catalog number: | GENTAUR-58be5ce6e67ba |
|---|---|
| Price: | 489 € |
| Supplier: | Bioss Polyclonal Antibodies |
| Product name: | Anti-c-Kit(Tyr568 + Tyr570), ALEXA Fluor 594 |
| Quantity: | 100 microliters |
| Related search: |
| Type: | Conjugated Primary Antibody |
|---|---|
| Conjugated with: | 594, ALEXA FLUOR® |
| Host organism: | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: | c-Kit Tyr568 + Tyr570 |
| Specificity: | This antibody reacts specifically with c-Kit(Tyr568 + Tyr570) |
| Modification: | Phosphorylation |
| Modification site: | Tyr568 + Tyr570 |
| Clonality: | Polyclonal Antibody |
| Clone: | Polyclonal Antibodies |
| Concentration: | 1ug per 1ul |
| Antigen Source: | KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr568 + Tyr570 |
| Gene ID: | 3815 |
| Applications: | IF(IHC-P) |
| Applications with corresponding dilutions: | IF(IHC-P)(1:50-200) |
| Cross reactive species: | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: | Ewing sarcoma and lung cancer, Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase, acute myeloid leukemia, and activation, apoptosis, c-Kit acts to regulate a variety of biological responses including cell proliferation, chemotaxis and adhesion, gastrointestinal stromal tumor, c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene |
| Purification method: | Purified by Protein A |
| Storage: | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | C Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, Stem cell factor receptor, Tyrosine-protein kinase Kit, c-Kit, p-c-Kit phospho Y568 + Y570, p145 c-kit, soluble KIT variant 1, tyrosine protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, c-Kit phospho Y568 + Y570 |
| Also known as: | c-Kit(Tyr568 + Tyr570) Antibody |
| Other name: | Anti-c-Kit(Tyr568 + Tyr570) |
| Advisory: | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: | For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | c-Kit(Tyr568 + Tyr570) |
| Short name: | Anti-c-Kit(Tyr568 + Tyr570) Fluor 594 |
| Label: | ALEXA |
| Alternative name: | ALEXA Fluor 594, antibody to-c-reagent(Tyr568 and Tyr570) |
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