Anti-c-Kit(Tyr568 + Tyr570), ALEXA Fluor 594

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Catalog number: GENTAUR-58be5ce6e67ba
Price: 489 €
Supplier: Bioss Polyclonal Antibodies
Product name: Anti-c-Kit(Tyr568 + Tyr570), ALEXA Fluor 594
Quantity: 100 microliters
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More details :

Type: Conjugated Primary Antibody
Conjugated with: 594, ALEXA FLUOR®
Host organism: Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide: c-Kit Tyr568 + Tyr570
Specificity: This antibody reacts specifically with c-Kit(Tyr568 + Tyr570)
Modification: Phosphorylation
Modification site: Tyr568 + Tyr570
Clonality: Polyclonal Antibody
Clone: Polyclonal Antibodies
Concentration: 1ug per 1ul
Antigen Source: KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr568 + Tyr570
Gene ID: 3815
Applications: IF(IHC-P)
Applications with corresponding dilutions: IF(IHC-P)(1:50-200)
Cross reactive species: Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details: However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information: Ewing sarcoma and lung cancer, Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase, acute myeloid leukemia, and activation, apoptosis, c-Kit acts to regulate a variety of biological responses including cell proliferation, chemotaxis and adhesion, gastrointestinal stromal tumor, c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene
Purification method: Purified by Protein A
Storage: 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission: 590nm/617nm
Synonyms: C Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, Stem cell factor receptor, Tyrosine-protein kinase Kit, c-Kit, p-c-Kit phospho Y568 + Y570, p145 c-kit, soluble KIT variant 1, tyrosine protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, c-Kit phospho Y568 + Y570
Also known as: c-Kit(Tyr568 + Tyr570) Antibody
Other name: Anti-c-Kit(Tyr568 + Tyr570)
Advisory: For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties: For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: c-Kit(Tyr568 + Tyr570)
Short name: Anti-c-Kit(Tyr568 + Tyr570) Fluor 594
Label: ALEXA
Alternative name: ALEXA Fluor 594, antibody to-c-reagent(Tyr568 and Tyr570)

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