| Long name: |
c-Kit(Tyr568 + Tyr570) Antibody |
| Also known as: |
c-Kit(Tyr568 + Tyr570) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
c-Kit Tyr568 + Tyr570 |
| Specificity: |
This is a highly specific antibody against c-Kit Tyr568 + Tyr570 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr568 + Tyr570 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr568 + Tyr570 |
| Gene ID number: |
3815 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Ewing sarcoma and lung cancer, Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase, acute myeloid leukemia, and activation, apoptosis, c-Kit acts to regulate a variety of biological responses including cell proliferation, chemotaxis and adhesion, gastrointestinal stromal tumor, c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, Stem cell factor receptor, Tyrosine-protein kinase Kit, c-Kit, p-c-Kit phospho Y568 + Y570, p145 c-kit, soluble KIT variant 1, tyrosine protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, c-Kit phospho Y568 + Y570 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
c-Kit(Tyr568 + Tyr570) |
| Short name: |
c-Kit(Tyr568 + Tyr570) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
c-reagent(Tyr568 and Tyr570) (Antibody to) |
| Alternative technique: |
antibodies |