| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Guanylin |
| Specificity: |
This antibody reacts specifically with Guanylin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Guanylin |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Guanylin and uroguanylin are secreted primarily in the stomach, Guanylin is also detected in plasma, Guanylin is an endogenous activator of intestinal guanylate cyclase, Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules, Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids, It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins, This 10kDa form is found circulating in the blood, and colon, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion, including guanylin and uroguanylin, intestine, The family of guanylin regulatory peptides |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GCAP-I, GUC2A_HUMAN, GUCA 2, GUCA2, GUCA2A, Guanylate cyclase activating protein 1, Guanylate cyclase activator 2A, Guanylate cyclase activator 2A guanylin 2 intestinal heat-stable, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, Guanylin, STARA, GapI |
| Also known as: |
Guanylin Polyclonal Antibody |
| Other name: |
Anti-Guanylin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Guanylin |
| Short name: |
Anti-Guanylin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Guanylin (polyclonal) |
| Alternative technique: |
polyclonals |