| Long name: |
Biotin Conjugated, Guanylin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Guanylin |
| Specificity: |
This is a highly specific antibody against Guanylin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Guanylin |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Guanylin and uroguanylin are secreted primarily in the stomach, Guanylin is also detected in plasma, Guanylin is an endogenous activator of intestinal guanylate cyclase, Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules, Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids, It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins, This 10kDa form is found circulating in the blood, and colon, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion, including guanylin and uroguanylin, intestine, The family of guanylin regulatory peptides |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
GCAP-I, GUC2A_HUMAN, GUCA 2, GUCA2, GUCA2A, Guanylate cyclase activating protein 1, Guanylate cyclase activator 2A, Guanylate cyclase activator 2A guanylin 2 intestinal heat-stable, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, Guanylin, STARA, GapI |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Guanylin Conjugated |
| Short name: |
Conjugated, Guanylin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Guanylin (Antibody to) |
| Alternative technique: |
antibodies |