| Long name: |
Guanylin Primary Polyclonal Antibody |
| Also known as: |
Guanylin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Guanylin |
| Specificity: |
This is a highly specific antibody against Guanylin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Guanylin |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Guanylin and uroguanylin are secreted primarily in the stomach, Guanylin is also detected in plasma, Guanylin is an endogenous activator of intestinal guanylate cyclase, Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules, Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids, It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins, This 10kDa form is found circulating in the blood, and colon, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion, including guanylin and uroguanylin, intestine, The family of guanylin regulatory peptides |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GCAP-I, GUC2A_HUMAN, GUCA 2, GUCA2, GUCA2A, Guanylate cyclase activating protein 1, Guanylate cyclase activator 2A, Guanylate cyclase activator 2A guanylin 2 intestinal heat-stable, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, Guanylin, STARA, GapI |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Guanylin |
| Short name: |
Guanylin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Guanylin (Antibody to) |
| Alternative technique: |
antibodies |