| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MCK10 |
| Specificity: |
This antibody reacts specifically with MCK10 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CD167a/MCK10 |
| Gene ID: |
780 |
| Swiss Prot: |
Q08345 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also plays a role in tumor cell invasion, Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases, MMP7 and MMP9, Phosphorylates PTPN11, Promotes smooth muscle cell migration, Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, Required for normal blastocyst implantation during pregnancy, Required for normal ear morphology and normal hearing (By similarity), and thereby contributes to arterial wound healing, and thereby facilitates cell migration and wound healing, cell migration, differentiation, for normal mammary gland differentiation and normal lactation, remodeling of the extracellular matrix, survival and cell proliferation, Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD167, CD167 antigen-like family member A, CD167a, Cell adhesion kinase, DDR, DDR1, Discoidin receptor tyrosine kinase, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, HGK2, MCK-10, MCK10, Mammary carcinoma kinase 10, NEP, NTRK4, PTK3, PTK3A, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, RTK6, TRK E, TRKE, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CAK |
| Also known as: |
MCK10 Polyclonal Antibody |
| Other name: |
Anti-MCK10 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MCK10 |
| Short name: |
Anti-MCK10 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MCK10 (polyclonal) |
| Alternative technique: |
polyclonals |