| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MCK10 Tyr513 |
| Specificity: |
This antibody reacts specifically with MCK10 (Tyr513) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr513 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human MCK10 around the phosphorylation site of Tyr513 |
| Gene ID: |
780 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing of this gene results in multiple transcript variants, In addition, In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, Its autophosphorylation is achieved by all collagens so far tested (type I to type VI), The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen, These molecules are involved in the regulation of cell growth, This gene is located on chromosome 6p21, This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain, and brain, and pediatric brain, differentiation and metabolism, esophageal, gastrointestinal tract, lung, ovarian, particularly in the kidney, this protein is significantly over-expressed in several human tumors from breast, 3 in proximity to several HLA class I genes, Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CAK, CD167, CD167a, Cell adhesion kinase, DDR, DDR 1, DDR1, DDR1CD 167, DDR1_HUMAN, Discoidin domain receptor, Discoidin receptor tyrosine kinase isoform a, EDDR 1, Epithelial discoidin domain receptor 1, Epithelial specic receptor kinase, Mammarian carcinoma kinase 10, NTRK 4, Neuroepithelial tyrosine kinase, Neurotrophic tyrosine kinase receptor type 4, PTK 3, PTK 3A protein tyrosine kinase 3A, RTK 6, Receptor tyrosine kinase NEP, TRK E, Tyrosine kinase receptor E, p-MCK10 phospho Y513, MCK10 phospho Y513 |
| Also known as: |
MCK10 (Tyr513) Polyclonal Antibody |
| Other name: |
Anti-MCK10 (Tyr513) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MCK10 (Tyr513) |
| Short name: |
Anti-MCK10 (Tyr513) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MCK10 (Tyr513) (polyclonal) |
| Alternative technique: |
polyclonals |