| Long name: |
Biotin Conjugated, MCK10 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MCK10 |
| Specificity: |
This is a highly specific antibody against MCK10 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
21-71/913 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CD167a/MCK10 |
| Gene ID number: |
780 |
| Swiss Prot: |
Q08345 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also plays a role in tumor cell invasion, Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases, MMP7 and MMP9, Phosphorylates PTPN11, Promotes smooth muscle cell migration, Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, Required for normal blastocyst implantation during pregnancy, Required for normal ear morphology and normal hearing (By similarity), and thereby contributes to arterial wound healing, and thereby facilitates cell migration and wound healing, cell migration, differentiation, for normal mammary gland differentiation and normal lactation, remodeling of the extracellular matrix, survival and cell proliferation, Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CD167, CD167 antigen-like family member A, CD167a, Cell adhesion kinase, DDR, DDR1, Discoidin receptor tyrosine kinase, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, HGK2, MCK-10, MCK10, Mammary carcinoma kinase 10, NEP, NTRK4, PTK3, PTK3A, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, RTK6, TRK E, TRKE, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CAK |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MCK10 Conjugated |
| Short name: |
Conjugated, MCK10 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, MCK10 (Antibody to) |
| Alternative technique: |
antibodies |