| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SMURF1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the SMURF1 antibody should be determined by the researcher |
| Intented use: |
This SMURF1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9HCE7 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants encoding different isoforms, It is mapped to 7q22, This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway, This protein plays a key roll in the regulation of cell motility, and cell polarity, cell signalling, 1, E3 ubiquitin-protein ligase SMURF1 is an enzyme that in humans is encoded by the SMURF1 gene |
| Immunogen: |
Amino acids DHNNRTTQFTDPRLHHIMNHQCQLKE of human SMURF1 were used as the immunogen for the SMURF1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SMURF1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SMURF1 |
| Short name: |
SMURF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SMAD specific E3 ubiquitin protein ligase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
R-SMAD binding, SMURF1 and IDBG-28871 and ENSG00000198742 and 57154, SMURF1 and IDBG-640859 and ENSBTAG00000007118 and, Smurf1 and IDBG-208404 and ENSMUSG00000038780 and 75788, nuclei, this GO :0000209 and protein polyubiquitination and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006611 and protein export from nucleus and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007398 and ectoderm development and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030279 and negative regulation of ossification and biological process this GO :0030424 and axon and cellular component this GO :0030509 and BMP signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0030579 and ubiquitin-dependent SMAD protein catabolic process and biological process this GO :0032801 and receptor catabolic process and biological process this GO :0034394 and protein localization to cell surface and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0048185 and activin binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070411 and I-SMAD binding and molecular function this GO :0070412 and R-SMAD binding and molecular function, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0016874 : ligase activity and also this GO :0048185 : activin binding and also this GO :0070411 : I-SMAD binding and also this GO :0070412 : R-SMAD binding, this GO :0005515 : protein binding, this GO :0016874 : ligase activity, this GO :0048185 : activin binding, this GO :0070411 : I-SMAD binding, this GO :0070412 : R-SMAD binding, SMAD specific E3 ubiquitin protein ligase 1 |
| Identity: |
16807 |
| Gene: |
SMURF1 |
More about : SMURF1 |
| Long gene name: |
SMAD specific E3 ubiquitin protein ligase 1 |
| Synonyms: |
KIAA1625 |
| Locus: |
7q22, 1 |
| Discovery year: |
2004-07-29 |
| GenBank acession: |
AB046845 |
| Entrez gene record: |
57154 |
| Pubmed identfication: |
10458166 |
| RefSeq identity: |
NM_020429 |
| Havana BLAST/BLAT: |
OTTHUMG00000150272 |