| Also known as: |
SMURF1 |
| Other names: |
E3 ubiquitin ligase SMURF1, E3 ubiquitin-protein ligase SMURF1, E3 ubiquitin-protein ligase SMURF1, SMAD specific E3 ubiquitin protein ligase 1, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1, SMAD-specific E3 ubiquitin-protein ligase 1, Smad ubiquitination regulatory factor 1, Smad-specific E3 ubiquitin ligase 1, hSMURF1, E3 ubiquitin-protein ligase SMURF1 isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SMURF1 |
| Other gene names: |
KIAA1625, N/A, SMURF1, hSMURF1, SMURF1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
1D7 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human SMURF1 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
35 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 1D7] (IgG2a, k) SMURF1 |
| Short name: |
Mouse Monoclonal [clone 1D7] (IgG2a, k) SMURF1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens SMAD specific E3 ubiquitin protein ligase 1 (Antibody to), Mouse monoclonal [clonality 1D7] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
R-SMAD binding, SMURF1 and IDBG-28871 and ENSG00000198742 and 57154, SMURF1 and IDBG-640859 and ENSBTAG00000007118 and, Smurf1 and IDBG-208404 and ENSMUSG00000038780 and 75788, nuclei, this GO :0000209 and protein polyubiquitination and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006611 and protein export from nucleus and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007398 and ectoderm development and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030279 and negative regulation of ossification and biological process this GO :0030424 and axon and cellular component this GO :0030509 and BMP signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0030579 and ubiquitin-dependent SMAD protein catabolic process and biological process this GO :0032801 and receptor catabolic process and biological process this GO :0034394 and protein localization to cell surface and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0048185 and activin binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070411 and I-SMAD binding and molecular function this GO :0070412 and R-SMAD binding and molecular function, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0016874 : ligase activity and also this GO :0048185 : activin binding and also this GO :0070411 : I-SMAD binding and also this GO :0070412 : R-SMAD binding, this GO :0005515 : protein binding, this GO :0016874 : ligase activity, this GO :0048185 : activin binding, this GO :0070411 : I-SMAD binding, this GO :0070412 : R-SMAD binding, SMAD specific E3 ubiquitin protein ligase 1 |
| Identity: |
16807 |
| Gene: |
SMURF1 |
More about : SMURF1 |
| Long gene name: |
SMAD specific E3 ubiquitin protein ligase 1 |
| Synonyms: |
KIAA1625 |
| Locus: |
7q22, 1 |
| Discovery year: |
2004-07-29 |
| GenBank acession: |
AB046845 |
| Entrez gene record: |
57154 |
| Pubmed identfication: |
10458166 |
| RefSeq identity: |
NM_020429 |
| Havana BLAST/BLAT: |
OTTHUMG00000150272 |