| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Eotaxin / CCL11 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
1-0, 1-0, 5ug/ml, 5ug/ml, ELISA : 0, Western blot: 0 |
| Notes: |
Optimal dilution of the CCL11 antibody should be determined by the researcher |
| Intented use: |
This CCL11 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P51671 |
| Purity: |
Antigen affinity |
| Description: |
CCR3 and CCR5, Chemokine receptors for which Eotaxin is a ligand include CCR2, Eotaxin selectively recruits eosinophils by inducing their chemotaxis, However, The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor, The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12, also known as Eotaxin, and therefore, is a small cytokine belonging to the CC chemokine family, is implicated in allergic responses, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3, CCL11 (Chemokine (C-C motif) ligand 11) |
| Immunogen: |
Amino acids 24-97 of human Eotaxin/CCL11 were used as the immunogen for the CCL11 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCL11 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Eotaxin / CCL11 |
| Short name: |
Eotaxin Antibody / CCL11 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Eotaxin (Antibody to) / chemokine (C-C motif) ligand 11 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCL11 and IDBG-40645 and ENSG00000172156 and 6356, CCL11 and IDBG-630948 and ENSBTAG00000004129 and 404072, Ccl11 and IDBG-204519 and ENSMUSG00000020676 and 20292, Extracellular, SCYA11, chemokine activity, this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002544 and chronic inflammatory response and biological process this GO :0002551 and mast cell chemotaxis and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007015 and actin filament organization and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008360 and regulation of cell shape and biological process this GO :0009314 and response to radiation and biological process this GO :0009615 and response to virus and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048245 and eosinophil chemotaxis and biological process this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0060763 and mammary duct terminal end bud growth and biological process this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0070670 and response to interleukin-4 and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity, chemokine (C-C motif) ligand 11 |
| Identity: |
10610 |
| Gene: |
CCL11 |
More about : CCL11 |
| Long gene name: |
C-C motif chemokine ligand 11 |
| Synonyms gene: |
SCYA11 |
| Synonyms gene name: |
member 11 (eotaxin) chemokine (C-C motif) ligand 11 , small inducible cytokine subfamily A (Cys-Cys) |
| Synonyms: |
eotaxin MGC22554 |
| Synonyms name: |
eotaxin-1 |
| Locus: |
17q12 |
| Discovery year: |
1996-04-24 |
| GenBank acession: |
AB063614 |
| Entrez gene record: |
6356 |
| Pubmed identfication: |
9169149 |
| RefSeq identity: |
NM_002986 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000132884 |