| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RANK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the RANK antibody should be determined by the researcher |
| Intented use: |
This RANK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O35305 |
| Purity: |
Antigen affinity |
| Description: |
(1997) mapped the RANK gene to 18q22, Anderson et al, By analysis of somatic cell and radiation hybrid panels, RANK is also expressed on dendritic cells and facilitates immune signaling, RANKL (Receptor Activator for NFkB Ligand) is found on the surface of stromal cells, also known as TRANCE Receptor, and T cells, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding, osteoblasts, 1, Receptor Activator of NFkB (RANK) |
| Immunogen: |
Amino acids 35-214 of mouse RANK were used as the immunogen for the RANK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RANK antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RANK |
| Short name: |
RANK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RANK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11908 |
| Gene: |
TNFRSF11A |
More about : TNFRSF11A |
| Long gene name: |
TNF receptor superfamily member 11a |
| Synonyms gene: |
PDB2 LOH18CR1 |
| Synonyms gene name: |
18, NFKB activator , activator of NFKB Paget disease of bone 2 loss of heterozygosity, chromosomal region 1 tumor necrosis factor receptor superfamily, member 11a, member 11a, tumor necrosis factor receptor superfamily |
| Synonyms: |
RANK CD265 FEO |
| Locus: |
18q21, 33 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF018253 |
| Entrez gene record: |
8792 |
| Pubmed identfication: |
9367155 10615125 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000132779 |
| Locus Specific Databases: |
LRG_194 |