| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PTCH1 (Patched) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the PTCH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This PTCH1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
5727 |
| Purity: |
Antigen affinity |
| Description: |
Additional splice variants have been described, Alternative splicing results in multiple transcript variants encoding different isoforms, BCNS or HPE7, Mutations of this gene have been associated with basal cell nevus syndrome, PTC, PTCH1 functions as a tumor suppressor, The protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as holoprosencephaly, as well as the desert hedgehog and indian hedgehog proteins, but their full length sequences and biological validity have not been determined, esophageal squamous cell carcinoma, is a member of the patched gene family, transitional cell carcinomas of the bladder, trichoepitheliomas, PTCH1 is also known as Patched |
| Immunogen: |
Human partial recombinant protein (AA 1219-1447) was used as the immunogen for this Patched / PTCH1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PTCH1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PTCH1 (Patched) |
| Short name: |
PTCH1 Antibody (Patched) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PTCH1 (Antibody to) (Patched) |
| Alternative technique: |
antibodies |
| Identity: |
9585 |
| Gene: |
PTCH1 |
More about : PTCH1 |
| Long gene name: |
patched 1 |
| Synonyms gene: |
NBCCS PTCH |
| Synonyms gene name: |
patched (Drosophila) homolog patched homolog (Drosophila) patched homolog 1 (Drosophila) |
| Synonyms: |
BCNS |
| Locus: |
9q22, 32 |
| Discovery year: |
1996-07-19 |
| GenBank acession: |
AI494442 |
| Entrez gene record: |
5727 |
| Pubmed identfication: |
8658145 |
| RefSeq identity: |
NM_000264 |
| Havana BLAST/BLAT: |
OTTHUMG00000020280 |
| Locus Specific Databases: |
LRG_515 |