| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LKB1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Variations in secondary/substrate sensitivities and test protocols may require the LKB1 antibody to be titrated for optimal performance |
| Intented use: |
This LKB1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
6794 |
| Purity: |
Antigen affinity |
| Description: |
It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways, STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), The STK11 gene, a necessary element in cell metabolism that is required for maintaining energy homeostasis, regulates cell polarity and functions as a tumour suppressor, which encodes a member of the serine/threonine kinase, Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene |
| Immunogen: |
Human partial recombinant protein (AA 62-430) was used as the immunogen for this LKB1 antibody |
| Storage: |
After reconstitution, Avoid repeated freeze/thaws, Celcius or lower, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, The lyophilized LKB1 antibody can be stored at 4oC to -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LKB1 |
| Short name: |
LKB1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LKB1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11389 |
| Gene: |
STK11 |
More about : STK11 |
| Long gene name: |
serine/threonine kinase 11 |
| Synonyms gene name: |
serine/threonine kinase 11 (Peutz-Jeghers syndrome) |
| Synonyms: |
PJS LKB1 |
| Synonyms name: |
polarization-related protein LKB1 |
| Locus: |
19p13, 3 |
| Discovery year: |
1998-01-21 |
| GenBank acession: |
U63333 |
| Entrez gene record: |
6794 |
| Pubmed identfication: |
9425897 |
| RefSeq identity: |
NM_000455 |
| Havana BLAST/BLAT: |
OTTHUMG00000180118 |
| Locus Specific Databases: |
LRG_319 |