| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Crk p38 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Crk antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Crk antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1398 |
| Purity: |
Antigen affinity |
| Description: |
It is mapped to 17p13, The N-terminal SH2 domain of Crk functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, The protein participates in the Reelin signaling cascade downstream of DAB1, This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins, Two alternative transcripts encoding different isoforms with distinct biological activity have been described, also known as p38, is a protein that in humans is encoded by the CRK gene, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, 3, CRK |
| Immunogen: |
Human partial recombinant protein (AA 2-246) was used as the immunogen for this Crk antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Crk antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Crk p38 |
| Short name: |
Crk Antibody p38 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Crk (Antibody to) p38 |
| Alternative technique: |
antibodies |