| Long name: |
HRP Conjugated, Crk p38 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Crk p38 |
| Specificity: |
This is a highly specific antibody against Crk p38 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Crk p38 /CrkII |
| Gene ID number: |
1398 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers, CrkI and CrkII are produced from the same crk gene by alternative splicing, In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth, It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, Crk p38 (CrkII) is an isoform of the protein Crk, Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Adapter molecule crk, Avian sarcoma virus CT10 v crk oncogene homolog, CRK isoform 2, CRK isoform II, CRKII, CrkII, Proto oncogene C crk, p38, v crk avian sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog avian, CRK |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
Crk p38 Conjugated |
| Short name: |
Conjugated, Crk p38 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, Crk p38 (Antibody to) |
| Alternative technique: |
antibodies |