Crk p38 Antibody

Catalog number:	bs-2763R Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Crk p38 Antibody
Quantity:	0.1ml
Related search:	crk antibody crkii oncogene homolog avian domains

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Long name:	Crk p38 Primary Polyclonal Antibody
Also known as:	Crk p38 PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Crk p38
Specificity:	This is a highly specific antibody against Crk p38
Modification(s):	None
Modification site(s):	Unmodified antibody
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Crk p38 /CrkII
Gene ID number:	1398
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers, CrkI and CrkII are produced from the same crk gene by alternative splicing, In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth, It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, Crk p38 (CrkII) is an isoform of the protein Crk, Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	Adapter molecule crk, Avian sarcoma virus CT10 v crk oncogene homolog, CRK isoform 2, CRK isoform II, CRKII, CrkII, Proto oncogene C crk, p38, v crk avian sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog avian, CRK
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Crk p38
Short name:	Crk p38 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Crk p38 (Antibody to)
Alternative technique:	antibodies

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• #antibody
• #crkii
• #oncogene
• #homolog
• #avian
• #domains