| known also as: |
HD3, RPD3, RPD3-2, SMAP45), Anti-HDAC3 (Histone Deacetylase 3 |
| known also as: |
HD3, RPD3, RPD3-2, SMAP45), HDAC3 (Histone Deacetylase 3 |
| known also as: |
HD3, RPD3, RPD3-2, SMAP45), HDAC3 (Histone Deacetylase 3 |
| known also as: |
HDAC3 |
| known also as: |
HD3, RPD3, RPD3-2, SMAP45), Anti -HDAC3 (Histone Deacetylase 3 |
| Other names: |
Histone deacetylase 3, OTTHUMP00000160029, RPD3-2, SMAP45, SMAP45, histone deacetylase 3, histone deacetylase 3, histone deacetylase 3 |
| Other gene names: |
HD3, HDAC3, N/A, RPD3, RPD3-2, HDAC3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human, Mouse, Rat, Chicken |
| Specificity and cross-reactivity: |
Expected to crossreact with Mouse (100% identity with immunogen), Rat (100% identity with immunogen) and Chicken (100% identity with immunogen) due to sequence homology, Species Crossreactivity: Crossreacts with Human, a 50kD band is observed, In HeLa |
| Purification method: |
Purified |
| Form/Appearance: |
0, 0, 05% sodium azide, 2% gelatin, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
HD3, RPD3, RPD3-2, SMAP45), HDAC3 (Histone Deacetylase 3 |
| Short name: |
HD3, RPD3, RPD3-2, SMAP45) Antibody, HDAC3 (Histone Deacetylase 3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HD3, RPD3, RPD3-2, SMAP45) (Antibody to), histone deacetylase 3 (Histone Deacetylase 3 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006476 and protein deacetylation and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008152 and metabolic process and biological process this GO :0016568 and chromatin modification and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030332 and cyclin binding and molecular function this GO :0031490 and chromatin DNA binding and molecular function this GO :0032041 and NAD-dependent histone deacetylase activity (H3-K14 specific) and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0033558 and protein deacetylase activity and molecular function this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0046970 and NAD-dependent histone deacetylase activity (H4-K16 specific) and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051225 and spindle assembly and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0070933 and histone H4 deacetylation and biological process this GO :0097372 and NAD-dependent histone deacetylase activity (H3-K18 specific) and molecular function, HD3 and RPD3 and RPD3-2, HDAC3 and IDBG-50725 and ENSG00000171720 and 8841, HDAC3 and IDBG-646121 and ENSBTAG00000017360 and 404125, Hdac3 and IDBG-140814 and ENSMUSG00000024454 and 15183, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, this GO :0000118 and histone deacetylase complex and cellular component this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005876 and spindle microtubule and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003714 : transcription corepressor activity and also this GO :0004407 : histone deacetylase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0016787 : hydrolase activity and also this GO :0019899 : enzyme binding and also this GO :0030332 : cyclin binding and also this GO :0031490 : chromatin DNA binding and also this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific) and also this GO :0033558 : protein deacetylase activity and also this GO :0042826 : histone deacetylase binding and also this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific) and also this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO :0003682 : chromatin binding, this GO :0003714 : transcription corepressor activity, this GO :0004407 : histone deacetylase activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0016787 : hydrolase activity, this GO :0019899 : enzyme binding, this GO :0030332 : cyclin binding, this GO :0031490 : chromatin DNA binding, this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific), this GO :0033558 : protein deacetylase activity, this GO :0042826 : histone deacetylase binding, this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific), this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), histone deacetylase 3 |
| Identity: |
4854 |
| Gene: |
HDAC3 |
More about : HDAC3 |
| Long gene name: |
histone deacetylase 3 |
| Synonyms: |
RPD3 HD3 RPD3-2 |
| Locus: |
5q31, 3 |
| Discovery year: |
1999-01-29 |
| GenBank acession: |
AF059650 |
| Entrez gene record: |
8841 |
| Pubmed identfication: |
9501169 9464271 |
| RefSeq identity: |
NM_003883 |
| Classification: |
Histone deacetylases, class I |
| Havana BLAST/BLAT: |
OTTHUMG00000129629 |