| Also known as: |
CD47 |
| Other names: |
Antigenic surface determinant protein OA3, CD47 antigen (Rh-related antigen, CD47 glycoprotein, CD47 molecule, CD_antigen: CD47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, Protein MER6, Rh-related antigen, antigen identified by monoclonal antibody 1D8, antigenic surface determinant protein OA3, integrin associated protein, integrin-associated protein, integrin-associated signal transducer, integrin-associated signal transducer), leukocyte surface antigen CD47, leukocyte surface antigen CD47 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD47 |
| Other gene names: |
CD47, IAP, IAP, MER6, MER6, OA3, CD47 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
2, B6H12 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD47, CD47 may play a role in membrane transport and/or integrin dependent signal transduction, CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix, It is important in memory formation and synaptic plasticity in the hippocampus, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, and in the modulation of integrins, is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail, originally named integrin-associated protein (IAP), This antibody reacts with Ig domain of CD47 protein |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Functional Studies |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD47/ IAP |
| Short name: |
CD47/ IAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD47 molecule/ IAP (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD47 and IDBG-48744 and ENSG00000196776 and 961, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, IAP and MER6 and OA3, Plasma membranes, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008228 and opsonization and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009617 and response to bacterium and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0070053 : thrombospondin receptor activity, this GO :0070053 : thrombospondin receptor activity, thrombospondin receptor activity, CD47 molecule |
| Identity: |
1682 |
| Gene: |
CD47 |
More about : CD47 |
| Long gene name: |
CD47 molecule |
| Synonyms gene: |
MER6 |
| Synonyms gene name: |
CD47 antigen (Rh-related antigen, integrin-associated signal transducer) |
| Synonyms: |
IAP OA3 |
| Synonyms name: |
antigen identified by monoclonal antibody 1D8 antigenic surface determinant protein OA3 integrin associated protein Rh-related antigen leukocyte surface antigen CD47 CD47 glycoprotein |
| Locus: |
3q13, 12 |
| Discovery year: |
1994-12-12 |
| Entrez gene record: |
961 |
| Pubmed identfication: |
8294396 2277087 |
| RefSeq identity: |
NM_001777 |
| Classification: |
Immunoglobulin like domain containing CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000044216 |