| known also as: |
CT (Melanoma Differentiation-Associated Protein 5, IFIH1), Interferon-Induced with Helicase C Domain Protein 1, Anti-MDA5 |
| known also as: |
CT (Melanoma Differentiation-Associated Protein 5, IFIH1), Interferon-Induced with Helicase C Domain Protein 1, MDA5 |
| known also as: |
CT (Melanoma Differentiation-Associated Protein 5, IFIH1), Interferon-Induced with Helicase C Domain Protein 1, MDA5 |
| known also as: |
MDA5 |
| known also as: |
CT (Melanoma Differentiation-Associated Protein 5, IFIH1), Interferon-Induced with Helicase C Domain Protein 1, Anti -MDA5 |
| Other names: |
CADM-140 autoantigen, CADM-140 autoantigen, Clinically amyopathic dermatomyositis autoantigen 140 kDa, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Helicard, Helicase with 2 CARD domains, Interferon-induced helicase C domain-containing protein 1, Interferon-induced with helicase C domain protein 1, MDA-5, Melanoma differentiation-associated protein 5, Murabutide down-regulated protein, OTTHUMP00000162935, RNA helicase-DEAD box protein 116, RNA helicase-DEAD box protein 116, clinically amyopathic dermatomyositis autoantigen 140 kDa, helicard, helicase with 2 CARD domains, interferon induced with helicase C domain 1, interferon-induced helicase C domain-containing protein 1, interferon-induced with helicase C domain protein 1, melanoma differentiation associated protein-5, melanoma differentiation-associated protein 5, murabutide down-regulated protein, melanoma differentiation associated protein-5 |
| Other gene names: |
Hlcd, IDDM19, IFIH1, MDA-5, MDA5, MDA5, MGC133047, RH116, IFIH1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
Species Crossreactivity: Mouse, Recognizes human MDA5 |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 02% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile glycerol (40-50%), aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
factors or kinases, increase , (an , Induced protein genes, at , enzyme , genetic transcription, level , of , of , or , other , production , protein) , the , the |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CT (Melanoma Differentiation-Associated Protein 5, IFIH1), Interferon with Helicase C Domain Protein 1, MDA5 |
| Short name: |
CT (Melanoma Differentiation-Associated Protein 5, IFIH1) Antibody, Interferon- with Helicase C Domain Protein 1, MDA5 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CT (Melanoma Differentiation-Associated Protein 5, Interferon-Induced including Helicase C Domain Protein 1, interferon induced including helicase C domain 1) (Antibody to), MDA5 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IFIH1 and IDBG-641195 and ENSBTAG00000008142 and 535490, IFIH1 and IDBG-73750 and ENSG00000115267 and 64135, Ifih1 and IDBG-174129 and ENSMUSG00000026896 and 71586, acting on acid anhydrides, acting on acid anhydrides and also this GO :0043021 : ribonucleoprotein complex binding, acting on acid anhydrides and molecular function this GO :0016925 and protein sumoylation and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0034344 and regulation of type III interferon production and biological process this GO :0039528 and cytoplasmic pattern recognition receptor signaling pathway in response to virus and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043021 and ribonucleoprotein complex binding and molecular function this GO :0045087 and innate immune response and biological process, hydrolase activity, nuclei, this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004386 and helicase activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0008270 and zinc ion binding and molecular function this GO :0009597 and detection of virus and biological process this GO :0009615 and response to virus and biological process this GO :0016032 and viral process and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0016817 and hydrolase activity, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0003677 : DNA binding and also this GO :0003725 : double-stranded RNA binding and also this GO :0003727 : single-stranded RNA binding and also this GO :0004386 : helicase activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008270 : zinc ion binding and also this GO :0016787 : hydrolase activity and also this GO :0016817 : hydrolase activity, this GO :0003677 : DNA binding, this GO :0003725 : double-stranded RNA binding, this GO :0003727 : single-stranded RNA binding, this GO :0004386 : helicase activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008270 : zinc ion binding, this GO :0016787 : hydrolase activity, this GO :0016817 : hydrolase activity, this GO :0043021 : ribonucleoprotein complex binding, interferon induced with helicase C domain 1 |
| Identity: |
18873 |
| Gene: |
IFIH1 |
More about : IFIH1 |
| Long gene name: |
interferon induced with helicase C domain 1 |
| Synonyms gene name: |
interferon induced with helicase C domain 1 interferon induced, with helicase C domain 1 |
| Synonyms: |
MDA-5 Hlcd MDA5 IDDM19 |
| Synonyms name: |
helicard melanoma differentiation-associated gene 5 |
| Locus: |
2q24, 2 |
| Discovery year: |
2004-06-25 |
| GenBank acession: |
AF095844 |
| Entrez gene record: |
64135 |
| RefSeq identity: |
NM_022168 |
| Classification: |
Caspase recruitment domain containing RNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000132055 |