| known also as: |
CDF, Cholinergic Differentiation Factor, D Factor, DIA, Differentiation-stimulating Factor, HILDA, MLPLI), Melanoma-derived LPL Inhibitor, Anti-Leukemia Inhibitory Factor (LIF |
| known also as: |
CDF, Cholinergic Differentiation Factor, D Factor, DIA, Differentiation-stimulating Factor, HILDA, MLPLI), Melanoma-derived LPL Inhibitor, Leukemia Inhibitory Factor (LIF |
| known also as: |
CDF, Cholinergic Differentiation Factor, D Factor, DIA, Differentiation-stimulating Factor, HILDA, MLPLI), Melanoma-derived LPL Inhibitor, Leukemia Inhibitory Factor (LIF |
| known also as: |
Leukemia Inhibitory Factor |
| known also as: |
CDF, Cholinergic Differentiation Factor, D Factor, DIA, Differentiation-stimulating Factor, HILDA, MLPLI), Melanoma-derived LPL Inhibitor, Anti -Leukemia Inhibitory Factor (LIF |
| Other names: |
D factor, D factor, Differentiation-stimulating factor, Leukemia inhibitory factor, MLPLI, Melanoma-derived LPL inhibitor, OTTHUMP00000198698, cholinergic differentiation factor, differentiation inhibitory activity, differentiation stimulating factor, differentiation-inducing factor, differentiation-stimulating factor, hepatocyte-stimulating factor III, human interleukin in DA cells, leukemia inhibitory factor, leukemia inhibitory factor (cholinergic differentiation factor), melanoma-derived LPL inhibitor, leukemia inhibitory factor |
| Other gene names: |
CDF, DIA, HILDA, HILDA, LIF, LIF |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Recognizes human LIF |
| Purification method: |
Affinity Purified by affinity chromatography |
| Form/Appearance: |
0, 0, 50% glycerol, 5mM EDTA, pH 7, 01% thimerosal, 2, 5% BSA, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CDF, Cholinergic Differentiation Factor, D Factor, DIA, Differentiation-stimulating Factor, HILDA, MLPLI), Melanoma-derived LPL Inhibitor, Leukemia Inhibitory Factor (LIF |
| Short name: |
CDF, Cholinergic Differentiation Factor, D Factor, DIA, Differentiation-stimulating Factor, HILDA, MLPLI) Antibody, Melanoma-derived LPL Inhibitor, Leukemia Inhibitory Factor (LIF |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CDF, Cholinergic Differentiation Factor, D Factor, DIA, Differentiation-stimulating Factor, HILDA, MLPLI) (Antibody to), Melanoma-derived lipoprotein lipase suppressor, Leukemia Inhibitory Factor (leukemia inhibitory factor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CDF and DIA and HILDA and MLPLI, Extracellular, Extracellular, HDLCQ11 and LIPD, LIF and IDBG-3968 and ENSG00000128342 and 3976, LIF and IDBG-636335 and ENSBTAG00000007424 and 280840, LPL and IDBG-634385 and ENSBTAG00000012855 and 280843, LPL and IDBG-9632 and ENSG00000175445 and 4023, Lif and IDBG-142317 and ENSMUSG00000034394 and 16878, Lpl and IDBG-159560 and ENSMUSG00000015568 and 16956, carboxylic ester hydrolase activity, growth factor activity, lipoprotein lipase, this GO :0001135 and RNA polymerase II transcription factor recruiting transcription factor activity and molecular function this GO :0001974 and blood vessel remodeling and biological process this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005146 and leukemia inhibitory factor receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006955 and immune response and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007566 and embryo implantation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0030324 and lung development and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0033141 and positive regulation of peptidyl-serine phosphorylation of STAT protein and biological process this GO :0042503 and tyrosine phosphorylation of Stat3 protein and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045835 and negative regulation of meiosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046697 and decidualization and biological process this GO :0046888 and negative regulation of hormone secretion and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048644 and muscle organ morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0048861 and leukemia inhibitory factor signaling pathway and biological process this GO :0048863 and stem cell differentiation and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0060426 and lung vasculature development and biological process this GO :0060463 and lung lobe morphogenesis and biological process this GO :0060707 and trophoblast giant cell differentiation and biological process this GO :0060708 and spongiotrophoblast differentiation and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0072108 and positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0072307 and regulation of metanephric nephron tubule epithelial cell differentiation and biological process this GO :1900182 and positive regulation of protein localization to nucleus and biological process this GO :1901676 and positive regulation of histone H3-K27 acetylation and biological process, this GO :0001135 : RNA polymerase II transcription factor recruiting transcription factor activity, this GO :0001135 : RNA polymerase II transcription factor recruiting transcription factor activity and also this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005146 : leukemia inhibitory factor receptor binding and also this GO :0008083 : growth factor activity, this GO :0001523 and retinoid metabolic process and biological process this GO :0004465 and lipoprotein lipase activity and molecular function this GO :0004620 and phospholipase activity and molecular function this GO :0004806 and triglyceride lipase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006633 and fatty acid biosynthetic process and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0007603 and phototransduction, this GO :0004465 : lipoprotein lipase activity, this GO :0004465 : lipoprotein lipase activity and also this GO :0004620 : phospholipase activity and also this GO :0004806 : triglyceride lipase activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0017129 : triglyceride binding and also this GO :0034185 : apolipoprotein binding and also this GO :0052689 : carboxylic ester hydrolase activity, this GO :0004620 : phospholipase activity, this GO :0004806 : triglyceride lipase activity, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding, this GO :0005125 : cytokine activity, this GO :0005146 : leukemia inhibitory factor receptor binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0008201 : heparin binding, this GO :0017129 : triglyceride binding, this GO :0034185 : apolipoprotein binding, this GO :0052689 : carboxylic ester hydrolase activity, visible light and biological process this GO :0008201 and heparin binding and molecular function this GO :0009409 and response to cold and biological process this GO :0009986 and cell surface and cellular component this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010886 and positive regulation of cholesterol storage and biological process this GO :0010890 and positive regulation of sequestering of triglyceride and biological process this GO :0016042 and lipid catabolic process and biological process this GO :0017129 and triglyceride binding and molecular function this GO :0019432 and triglyceride biosynthetic process and biological process this GO :0019433 and triglyceride catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031225 and anchored component of membrane and cellular component this GO :0034185 and apolipoprotein binding and molecular function this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034371 and chylomicron remodeling and biological process this GO :0034372 and very-low-density lipoprotein particle remodeling and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042627 and chylomicron and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0052689 and carboxylic ester hydrolase activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process, leukemia inhibitory factor |
| Identity: |
6596 |
| Gene: |
LIF |
More about : LIF |
| Long gene name: |
leukemia inhibitory factor |
| Synonyms: |
CDF DIA HILDA |
| Synonyms name: |
differentiation inhibitory activity differentiation-inducing factor hepatocyte-stimulating factor III cholinergic differentiation factor human interleukin in DA cells |
| Locus: |
22q12, 2 |
| Discovery year: |
1989-06-11 |
| Entrez gene record: |
3976 |
| Pubmed identfication: |
1714745 8058719 |
| RefSeq identity: |
NM_002309 |
| Classification: |
Endogenous ligands Interleukin 6 cytokine family |
| Havana BLAST/BLAT: |
OTTHUMG00000150910 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |