| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10 |
| known also as: |
Rabbit PAb (IgG) to Human CASP10 / Caspase 10 |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens CASP10 / Caspase 10 |
| known also as: |
CASP10 / Caspase 10 |
| known also as: |
ALPS2, Apoptotic protease Mch-4, CASP-10, CASP10, Caspase 10, Caspase 10, Caspase-10, FADD-like ICE2, FLICE2, Human CASP10, ICE-like apoptotic protease 4, MCH4, Anti-CASP10 / Caspase 10 Antibody (aa430-479) IHC-plus |
| Other names: |
Apoptotic protease Mch-4, CASP-10, Caspase-10, Caspase-10 subunit p12, FADD-like ICE2, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, ICE-like apoptotic protease 4Cleaved into the following 2 chains:Caspase-10 subunit p23/17, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, apoptotic protease MCH-4, caspase 10, caspase 10, caspase-10, interleukin-1B-converting enzyme 2, caspase-10 isoform 3 preproprotein |
| Gene name: |
CASP10 |
| Other gene names: |
ALPS2, CASP-10, CASP10, FLICE2, FLICE2, MCH4, MCH4, CASP10 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Caspase 10 Antibody detects endogenous levels of total Caspase 10 protein |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 150 mM sodium chloride, 50% glycerol, Ca2+), pH 7, 02% sodium azide, 4, PBS (without Mg2+ |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
for up to one year, Store productone should be stored at -20 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb CASP10 / Caspase 10 |
| Short name: |
PAb (IgG) CASP10 / Caspase 10 |
| Technique: |
IgGs, IgG |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
apoptosis-related cysteine peptidase / caspase 10, sapiens caspase 10, polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
immunoglobulins |
| Alternative to gene target: |
ALPS2 and FLICE2 and MCH4, CASP10 and IDBG-78470 and ENSG00000003400 and 843, Plasma membranes, apoptosis-related cysteine peptidase, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0031265 and CD95 death-inducing signaling complex and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0035877 and death effector domain binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097199 and cysteine-type endopeptidase activity involved in apoptotic signaling pathway and molecular function this GO :0097342 and ripoptosome and cellular component, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0035877 : death effector domain binding and also this GO :0097199 : cysteine-type endopeptidase activity involved in apoptotic signaling pathway, this GO :0005515 : protein binding, this GO :0008234 : cysteine-type peptidase activity, this GO :0031625 : ubiquitin protein ligase binding, this GO :0035877 : death effector domain binding, this GO :0097199 : cysteine-type endopeptidase activity involved in apoptotic signaling pathway, caspase 10 |
| Identity: |
1500 |
| Gene: |
CASP10 |
More about : CASP10 |
| Long gene name: |
caspase 10 |
| Synonyms gene name: |
apoptosis-related cysteine peptidase , apoptosis-related cysteine protease caspase 10, caspase 10 |
| Synonyms: |
MCH4 |
| Locus: |
2q33, 1 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
U60519 |
| Entrez gene record: |
843 |
| Pubmed identfication: |
8755496 |
| RefSeq identity: |
NM_032977 |
| Classification: |
Caspases Death effector domain containing Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000132818 |
| Locus Specific Databases: |
CASP10base: Mutation registry for Autoimmune lymphoproliferative syndrome, type II (ALPS2) LRG_33 |