| known also as: |
Anti-Rabbit Polyclonal (IgG) to Mouse CASP2 / Caspase 2 |
| known also as: |
Rabbit PAb (IgG) to Murine CASP2 / Caspase 2 |
| known also as: |
Lapin Polyclonal (IgG) to Mus musculus CASP2 / Caspase 2 |
| known also as: |
CASP2 / Caspase 2 |
| known also as: |
CASP-2, CASP2, Caspase 2, Caspase 2, Caspase-2, ICH1, Mouse CASP2, NEDD-2, NEDD2, PPP1R57, Protease ICH-1, Anti-CASP2 / Caspase 2 Antibody IHC-plus |
| Other names: |
Caspase-2, Caspase-2 subunit p12, Caspase-2 subunit p13, NEDD-2, Neural precursor cell expressed developmentally down-regulated protein 2, Protease ICH-1Cleaved into the following 3 chains:Caspase-2 subunit p18, apoptosis-related cysteine peptidase, caspase 2, caspase-2, neural precursor cell expressed developmentally down-regulated protein 2, protease ICH-1, protein phosphatase 1, regulatory subunit 57, caspase-2 isoform 1 preproprotein |
| Gene name: |
CASP2 |
| Other gene names: |
CASP-2, CASP-2, CASP2, ICH1, ICH1, NEDD-2, NEDD-2, NEDD2, NEDD2, PPP1R57, CASP2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
In human samples, Mouse small intestine lysate can be used as a positive control, it also detects a 30 kD intermediate fragment, Detects the full length and small subunit of caspase-2 |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, 0, 30% glycerol, pH 7, 01% Thimerosal, 2, 5% BSA, PBS |
| Concentration: |
2 mg/ml |
| Storage and shipping: |
Short term: Store productone at -20 degrees Celsius, Long term: -70 degree C |
| Tested for:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum  |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name: |
Mus musculus |
| Gene target: |
PAb CASP2 / Caspase 2 |
| Short name: |
PAb (IgG) Mouse CASP2 / Caspase 2 Antibody |
| Technique: |
IgGs, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Mouses, Mouse |
| Alternative name: |
apoptosis-related cysteine peptidase / caspase 2 (Antibody to), polyclonal (Immunoglobulin G) to Mouse caspase 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CASP-2 and ICH1 and NEDD-2 and NEDD2 and PPP1R57, CASP2 and IDBG-45836 and ENSG00000106144 and 835, Casp2 and IDBG-141522 and ENSMUSG00000029863 and 12366, apoptosis-related cysteine peptidase, cysteine-type endopeptidase activity involved in apoptotic process, nuclei, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007420 and brain development and biological process this GO :0007568 and aging and biological process this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0016020 and membrane and cellular component this GO :0016485 and protein processing and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0035234 and ectopic germ cell programmed cell death and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0097153 and cysteine-type endopeptidase activity involved in apoptotic process and molecular function this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097194 and execution phase of apoptosis and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, this GO :0001554 and luteolysis and biological process this GO :0003407 and neural retina development and biological process this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0019899 : enzyme binding and also this GO :0019904 : protein domain specific binding and also this GO :0097153 : cysteine-type endopeptidase activity involved in apoptotic process, this GO :0005515 : protein binding, this GO :0008234 : cysteine-type peptidase activity, this GO :0019899 : enzyme binding, this GO :0019904 : protein domain specific binding, this GO :0097153 : cysteine-type endopeptidase activity involved in apoptotic process, 103474 and IDBG-636898 and ENSBTAG00000018159 and 531419, caspase 2 |
| Identity: |
1503 |
| Gene: |
CASP2 |
More about : CASP2 |
| Long gene name: |
caspase 2 |
| Synonyms gene: |
NEDD2 |
| Synonyms gene name: |
apoptosis-related cysteine peptidase , developmentally down-regulated 2 caspase 2, neural precursor cell expressed |
| Synonyms: |
ICH1 PPP1R57 MGC2181 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 57 |
| Locus: |
7q34 |
| Discovery year: |
1994-01-21 |
| GenBank acession: |
AK096245 BC002427 BM998653 BX537669 CB988674 U13021 |
| Entrez gene record: |
835 |
| Pubmed identfication: |
7789948 8780721 19075813 |
| RefSeq identity: |
NM_032982 |
| Classification: |
Caspase recruitment domain containing Protein phosphatase 1 regulatory subunits Caspases |
| Havana BLAST/BLAT: |
OTTHUMG00000023641 |