| Also known as: |
NPHS1 / Nephrin |
| Other names: |
Finnish type (nephrin), Nephrin, Renal glomerulus-specific cell adhesion receptor, congenital, nephrin, nephrosis 1, renal glomerulus-specific cell adhesion receptor, nephrin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
NPHS1 |
| Other gene names: |
CNF, NPHN, NPHN, NPHS1, nephrin, NPHS1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgM, k |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human Nephrin |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 09% sodium azide, Ascites |
| Storage and shipping: |
For long term storage For optimal long term storage, for up to 6 months, the antibody should be kept at -20 degrees Celsius, Maintain refrigerated at the antibodys should be kept in the range of 1-7 degrees Celsius |
| Tested applications:: |
Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, IgM is by far the physically largest antibody in the human circulatory system, Immunoglobulin M, It is the first antibody to appear in response to initial exposure to an antigen, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, is a basic , or , plasma, primarily , saliva, urine, , (Homo sapiens, B cells, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, IgM , antibody , for short, humans , ssp, that is produced by |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal , k) NPHS1 / Nephrin |
| Short name: |
Mouse Monoclonal (IgM, k) NPHS1 / Nephrin Antibody |
| Technique: |
IgMs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgM |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
Finnish classification (nephrin) / Nephrin (Antibody to), congenital, sapiens nephrosis 1, Mouse monoclonal (Immunoglobulin M, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CNF and nephrin and NPHN, Finnish type (nephrin), NPHS1 and IDBG-45496 and ENSG00000161270 and 4868, NPHS1 and IDBG-636002 and ENSBTAG00000007821 and 519706, Nphs1 and IDBG-169263 and ENSMUSG00000006649 and 54631, Plasma membranes, alpha-actinin binding, congenital, this GO :0000165 and MAPK cascade and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007254 and JNK cascade and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0007520 and myoblast fusion and biological process this GO :0007588 and excretion and biological process this GO :0016020 and membrane and cellular component this GO :0017022 and myosin binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0030507 and spectrin binding and molecular function this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0032836 and glomerular basement membrane development and biological process this GO :0036057 and slit diaphragm and cellular component this GO :0042995 and cell projection and cellular component this GO :0043234 and protein complex and cellular component this GO :0044062 and regulation of excretion and biological process this GO :0045121 and membrane raft and cellular component this GO :0051393 and alpha-actinin binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072015 and glomerular visceral epithelial cell development and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0017022 : myosin binding and also this GO :0019904 : protein domain specific binding and also this GO :0030507 : spectrin binding and also this GO :0051393 : alpha-actinin binding, this GO :0017022 : myosin binding, this GO :0019904 : protein domain specific binding, this GO :0030507 : spectrin binding, this GO :0051393 : alpha-actinin binding, nephrosis 1 |
| Identity: |
7908 |
| Gene: |
NPHS1 |
More about : NPHS1 |
| Long gene name: |
NPHS1, nephrin |
| Synonyms gene name: |
Finnish type (nephrin) , congenital, nephrosis 1 |
| Synonyms: |
CNF NPHN |
| Locus: |
19q13, 12 |
| Discovery year: |
1994-12-14 |
| Entrez gene record: |
4868 |
| Pubmed identfication: |
9915943 9660941 |
| Classification: |
Fibronectin type III domain containing C2-set domain containing V-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180689 |
| Locus Specific Databases: |
LRG_693 |