| Also known as: |
ACTA1 / ASMA |
| Other names: |
Actin, Alpha-actin-1, actin, actin, alpha 1, alpha skeletal muscle, alpha skeletal muscle, alpha skeletal muscle, nemaline myopathy type 3, skeletal muscle, actin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ACTA1 |
| Gene name synonims: |
ASMA |
| Other gene names: |
ACTA, ACTA, ACTA1, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3, ACTA1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgM, k |
| Clone: |
5C5, C7, F8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Frog, Guinea pig, Human (Homo sapiens), Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Sheep, the reactivity of the antibody may extend to other species which are not listed hereby, Bovine |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N-terminal decapeptide |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
Sourced in Ascites, pH 7, with 0, 09% Sodium Azide, 10mM PBS, 2% BSA and 0, 4 |
| Concentration: |
2 mg/ml |
| Storage and shipping: |
Freezing of the antibody is not recommended, the antibody is stable for 2 years when stored at +4 degrees Celsius |
| Tested applications:: |
Immunofluorescence (IF), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, IgM is by far the physically largest antibody in the human circulatory system, Immunoglobulin M, It is the first antibody to appear in response to initial exposure to an antigen, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, is a basic , or , plasma, primarily , saliva, urine, , (Homo sapiens, B cells, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, IgM , antibody , for short, humans , ssp, that is produced by |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
C7] , F8, Monoclonal [ 5C5, k) ACTA1 / ASMA |
| Short name: |
C7] (IgM, F8, Mouse Monoclonal [clone 5C5, k) ACTA1 / ASMA Antibody |
| Technique: |
IgMs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgM |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
procoagulant component, sapiens ACTA1 / ASMA (Antibody to), Mouse monoclonal [clonality 5C5, coagulation factor VIII, complement component 7] (Immunoglobulin M, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AHF and DXS1253E and F8B and F8C and FVIII and HEMA, BT, C7 and IDBG-18519 and ENSG00000112936 and 730, C7 and IDBG-259737 and ENSMUSG00000079105 and 109828, Extracellular, Extracellular, F8 and IDBG-157124 and ENSMUSG00000031196 and 14069, F8 and IDBG-632125 and ENSBTAG00000010726 and 100271720, F8 and IDBG-92134 and ENSG00000185010 and 2157, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0019835 and cytolysis and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, coagulation factor VIII, intrinsic pathway and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0030168 and platelet activation and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0055114 and oxidation-reduction process and biological process, oxidoreductase activity, procoagulant component, protein binding, this GO :0002576 and platelet degranulation and biological process this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006953 and acute-phase response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0007597 and blood coagulation, this GO :0004252 : serine-type endopeptidase activity, this GO :0004252 : serine-type endopeptidase activity and also this GO :0005507 : copper ion binding and also this GO :0005515 : protein binding and also this GO :0016491 : oxidoreductase activity, this GO :0005507 : copper ion binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0006883 and cellular sodium ion homeostasis and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0016491 : oxidoreductase activity, 69954 and IDBG-629869 and ENSBTAG00000011766 and 507339, complement component 7 |
| Identity: |
129 |
| Gene: |
ACTA1 |
More about : ACTA1 |
| Long gene name: |
actin, alpha 1, skeletal muscle |
| Synonyms gene: |
ACTA |
| Synonyms: |
NEM3 |
| Synonyms name: |
nemaline myopathy type 3 |
| Locus: |
1q42, 13 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
J00068 |
| Entrez gene record: |
58 |
| Pubmed identfication: |
10072583 6865942 |
| RefSeq identity: |
NM_001100 |
| Classification: |
Actins |
| Havana BLAST/BLAT: |
OTTHUMG00000038006 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy pages LRG_429 |