| Also known as: |
SMAD6 |
| Other names: |
6, MAD homolog 6, Mothers against decapentaplegic homolog 6, SMAD, SMAD 6, SMAD family member 6, SMAD family member 6, Smad6, drosophila, hSMAD6, homolog of, mothers against DPP homolog 6, mothers against decapentaplegic, mothers against decapentaplegic homolog 6, mothers against decapentaplegic homolog 6 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SMAD6 |
| Other gene names: |
AOVD2, HsT17432, MAD homolog 6, MADH6, MADH6, MADH7, Mothers against DPP homolog 6, SMAD 6, SMAD6, Smad6, hSMAD6, SMAD6 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b, k |
| Clone: |
4F3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 4, PBS |
| Concentration: |
42 mg/ml |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 4F3] (IgG2b, k) SMAD6 |
| Short name: |
Mouse Monoclonal [clone 4F3] (IgG2b, k) SMAD6 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens SMAD family member 6 (Antibody to), Mouse monoclonal [clonality 4F3] (IgG2b, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AOVD2 and HsT17432 and MADH6 and MADH7, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006955 and immune response and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007352 and zy this GO tic specification of dorsal/ventral axis and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010991 and negative regulation of SMAD protein complex assembly and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0030617 and transforming growth factor beta receptor, SMAD6 and IDBG-18304 and ENSG00000137834 and 4091, SMAD6 and IDBG-645465 and ENSBTAG00000000625 and 511279, Smad6 and IDBG-175757 and ENSMUSG00000036867 and 17130, inhibitory cytoplasmic mediator activity, inhibitory cytoplasmic mediator activity and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0034713 : type I transforming growth factor beta receptor binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046872 : metal ion binding and also this GO :0070410 : co-SMAD binding and also this GO :0070411 : I-SMAD binding and also this GO :0070412 : R-SMAD binding and also this GO :0070698 : type I activin receptor binding, inhibitory cytoplasmic mediator activity and molecular function this GO :0031589 and cell-substrate adhesion and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0034713 and type I transforming growth factor beta receptor binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043627 and response to estrogen and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0060394 and negative regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0070410 and co-SMAD binding and molecular function this GO :0070411 and I-SMAD binding and molecular function this GO :0070412 and R-SMAD binding and molecular function this GO :0070698 and type I activin receptor binding and molecular function, nuclei, this GO :0001657 and ureteric bud development and biological process this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003682 : chromatin binding, this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0030617 : transforming growth factor beta receptor, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0030617 : transforming growth factor beta receptor, this GO :0031625 : ubiquitin protein ligase binding, this GO :0034713 : type I transforming growth factor beta receptor binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046872 : metal ion binding, this GO :0070410 : co-SMAD binding, this GO :0070411 : I-SMAD binding, this GO :0070412 : R-SMAD binding, this GO :0070698 : type I activin receptor binding, transforming growth factor beta receptor, SMAD family member 6 |
| Identity: |
6772 |
| Gene: |
SMAD6 |
More about : SMAD6 |
| Long gene name: |
SMAD family member 6 |
| Synonyms gene: |
MADH7 MADH6 |
| Synonyms gene name: |
MAD, mothers against DPP homolog 6 (Drosophila) , mothers against decapentaplegic homolog 6 (Drosophila) SMAD |
| Synonyms: |
HsT17432 |
| Locus: |
15q22, 31 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
BC012986 |
| Entrez gene record: |
4091 |
| Pubmed identfication: |
9256479 |
| RefSeq identity: |
NM_005585 |
| Classification: |
SMAD family |
| Havana BLAST/BLAT: |
OTTHUMG00000133218 |
| Locus Specific Databases: |
The Globin Gene Server |