| Also known as: |
SYK |
| Other names: |
Spleen tyrosine kinase, Tyrosine-protein kinase SYK, p72-Syk, spleen tyrosine kinase, tyrosine-protein kinase SYK, tyrosine-protein kinase SYK isoform Syk(L) |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SYK |
| Other gene names: |
N/A, SYK, p72-Syk, SYK |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b, k |
| Clone: |
12000 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
0, 0, and 50% glycerol, 01% BSA, 03% sodium azide, 15M NaCl, HEPES with 0 |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 12E3] (IgG2b, k) SYK |
| Short name: |
Mouse Monoclonal [clone 12E3] (IgG2b, k) SYK Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens spleen tyrosine kinase (Antibody to), Mouse monoclonal [clonality 12E3] (IgG2b, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, SYK and IDBG-637026 and ENSBTAG00000004767 and 515515, SYK and IDBG-75571 and ENSG00000165025 and 6850, Syk and IDBG-152695 and ENSMUSG00000021457 and 20963, p72-Syk, this GO :0000187 and activation of MAPK activity and biological process this GO :0001525 and angiogenesis and biological process this GO :0001820 and serotonin secretion and biological process this GO :0001945 and lymph vessel development and biological process this GO :0002250 and adaptive immune response and biological process this GO :0002281 and macrophage activation involved in immune response and biological process this GO :0002283 and neutrophil activation involved in immune response and biological process this GO :0002366 and leukocyte activation involved in immune response and biological process this GO :0002554 and serotonin secretion by platelet and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007167 and enzyme linked receptor protein signaling pathway and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0007596 and blood coagulation and biological process this GO :0008283 and cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010543 and regulation of platelet activation and biological process this GO :0016032 and viral process and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019901 : protein kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901 : protein kinase binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019370 and leukotriene biosynthetic process and biological process this GO :0019815 and B cell receptor complex and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0032009 and early pha this GO some and cellular component this GO :0032928 and regulation of superoxide anion generation and biological process this GO :0033630 and positive regulation of cell adhesion mediated by integrin and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042742 and defense response to bacterium and biological process this GO :0043234 and protein complex and cellular component this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0043313 and regulation of neutrophil degranulation and biological process this GO :0043366 and beta selection and biological process this GO :0045087 and innate immune response and biological process this GO :0045401 and positive regulation of interleukin-3 biosynthetic process and biological process this GO :0045425 and positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process and biological process this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0045588 and positive regulation of gamma-delta T cell differentiation and biological process this GO :0045780 and positive regulation of bone resorption and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048514 and blood vessel morphogenesis and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050764 and regulation of pha this GO cytosis and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0070372 and regulation of ERK1 and ERK2 cascade and biological process this GO :0071226 and cellular response to molecule of fungal origin and biological process this GO :0090237 and regulation of arachidonic acid secretion and biological process this GO :0090330 and regulation of platelet aggregation and biological process, spleen tyrosine kinase |
| Identity: |
11491 |
| Gene: |
SYK |
More about : SYK |
| Long gene name: |
spleen associated tyrosine kinase |
| Synonyms gene name: |
spleen tyrosine kinase |
| Locus: |
9q22, 2 |
| Discovery year: |
1994-12-13 |
| GenBank acession: |
L28824 |
| Entrez gene record: |
6850 |
| Pubmed identfication: |
8082894 1423621 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020200 |