| Also known as: |
Vitamin D Receptor / VDR |
| Other names: |
1, 1, Nuclear receptor subfamily 1 group I member 1, Vitamin D3 receptor, nuclear receptor subfamily 1 group I member 1, protein phosphatase 1, regulatory subunit 163, vitamin D (1, vitamin D nuclear receptor variant 1, vitamin D3 receptor, 25- dihydroxyvitamin D3) receptor, 25-dihydroxyvitamin D3 receptor, 25-dihydroxyvitamin D3 receptor, vitamin D3 receptor isoform VDRA |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
VDR |
| Other gene names: |
NR1I1, NR1I1, PPP1R163, VDR, VDR, VDR |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
2F4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 4, PBS |
| Concentration: |
42 mg/ml |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2F4] (IgG2a, k) Vitamin D Receptor / VDR |
| Short name: |
Mouse Monoclonal [clone 2F4] (IgG2a, k) Vitamin D Receptor / VDR Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens Vitamin D Receptor / vitamin D (1, 25- dihydroxyvitamin D3) receptor (Antibody to), Mouse monoclonal [clonality 2F4] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007165 and signal transduction and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007595 and lactation and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008434 and vitamin D3 receptor activity and molecular function this GO :0009887 and organ morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010839 and negative regulation of keratinocyte proliferation and biological process this GO :0010980 and positive regulation of vitamin D 24-hydroxylase activity and biological process this GO :0038183 and bile acid signaling pathway and biological process this GO :0038186 and lithocholic acid receptor activity and molecular function this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045618 and positive regulation of keratinocyte differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046697 and decidualization and biological process this GO :0046965 and retinoid X receptor binding and molecular function this GO :0050892 and intestinal absorption and biological process this GO :0060058 and positive regulation of apoptotic process involved in mammary gland involution and biological process this GO :0060558 and regulation of calcidiol 1-monooxygenase activity and biological process this GO :0060745 and mammary gland branching involved in pregnancy and biological process this GO :0070561 and vitamin D receptor signaling pathway and biological process this GO :0070644 and vitamin D response element binding and molecular function this GO :1902098 and calcitriol binding and molecular function this GO :1902121 and lithocholic acid binding and molecular function, NR1I1 and PPP1R163, VDR and IDBG-29237 and ENSG00000111424 and 7421, VDR and IDBG-633008 and ENSBTAG00000016414 and 533656, Vdr and IDBG-179227 and ENSMUSG00000022479 and 22337, lithocholic acid binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0001501 and skeletal system development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003707 : steroid hormone receptor activity and also this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0008434 : vitamin D3 receptor activity and also this GO :0038186 : lithocholic acid receptor activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046965 : retinoid X receptor binding and also this GO :0070644 : vitamin D response element binding and also this GO :1902098 : calcitriol binding and also this GO :1902121 : lithocholic acid binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003707 : steroid hormone receptor activity, this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0008434 : vitamin D3 receptor activity, this GO :0038186 : lithocholic acid receptor activity, this GO :0043565 : sequence-specific DNA binding, this GO :0046965 : retinoid X receptor binding, this GO :0070644 : vitamin D response element binding, this GO :1902098 : calcitriol binding, this GO :1902121 : lithocholic acid binding, 25- dihydroxyvitamin D3) receptor, vitamin D (1 |
| Identity: |
12679 |
| Gene: |
VDR |
More about : VDR |
| Long gene name: |
vitamin D (1, 25- dihydroxyvitamin D3) receptor |
| Synonyms: |
NR1I1 PPP1R163 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 163 |
| Locus: |
12q13, 11 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
J03258 |
| Entrez gene record: |
7421 |
| Pubmed identfication: |
1662663 |
| Classification: |
Nuclear hormone receptors Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000169890 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |