| Also known as: |
GHRL / Ghrelin |
| Other names: |
Appetite-regulating hormone, Ghrelin, Ghrelin-28, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Obestatin, Protein M46Cleaved into the following 3 chains:Ghrelin-27, appetite-regulating hormone, ghrelin, ghrelin/obestatin preprohormone, ghrelin/obestatin prepropeptide, growth hormone secretagogue receptor ligand, growth hormone-releasing peptide, motilin-related peptide, prepro-appetite regulatory hormone, appetite-regulating hormone isoform 1 preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
GHRL |
| Other gene names: |
GHRL, Ghrelin, MTLRP, MTLRP, GHRL |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
2F4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human GHRL |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| Description: |
GHRL is , Ghrelin is regulating the , obestatin prepropeptide or , , GHRL gene, Ghrelin, a , appetite, central nervous system regulating , distribution and rate of use of body energy, from ghrelinergic cells in the gastrointestinal tract, in the , lenomorelin , neuropeptide |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2F4] (IgG2a, k) GHRL / Ghrelin |
| Short name: |
Mouse Monoclonal [clone 2F4] (IgG2a, k) GHRL / Ghrelin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens ghrelin/obestatin prepropeptide / Ghrelin (Antibody to), Mouse monoclonal [clonality 2F4] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GHRL and IDBG-18011 and ENSG00000157017 and 51738, GHRL and IDBG-646311 and ENSBTAG00000012328 and 281192, Ghrl and IDBG-178411 and ENSMUSG00000064177 and 58991, REM sleep and biological process this GO :0042536 and negative regulation of tumor necrosis factor biosynthetic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043400 and cortisol secretion and biological process this GO :0043627 and response to estrogen and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045409 and negative regulation of interleukin-6 biosynthetic process and biological process this GO :0046010 and positive regulation of circadian sleep/wake cycle, ghrelin receptor binding, non-REM sleep and biological process this GO :0046676 and negative regulation of insulin secretion and biological process this GO :0046697 and decidualization and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0051216 and cartilage development and biological process this GO :0051461 and positive regulation of corticotropin secretion and biological process this GO :0051464 and positive regulation of cortisol secretion and biological process this GO :0051965 and positive regulation of synapse assembly and biological process this GO :0060079 and regulation of excitatory postsynaptic membrane potential and biological process this GO :0060124 and positive regulation of growth hormone secretion and biological process this GO :0060399 and positive regulation of growth hormone receptor signaling pathway and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0001664 and G-protein coupled receptor binding and molecular function this GO :0001696 and gastric acid secretion and biological process this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0005179 and hormone activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0006006 and glucose metabolic process and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0008154 and actin polymerization or depolymerization and biological process this GO :0008343 and adult feeding behavior and biological process this GO :0009725 and response to hormone and biological process this GO :0009755 and hormone-mediated signaling pathway and biological process this GO :0016358 and dendrite development and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0016608 and growth hormone-releasing hormone activity and molecular function this GO :0030252 and growth hormone secretion and biological process this GO :0030296 and protein tyrosine kinase activator activity and molecular function this GO :0030424 and axon and cellular component this GO :0031768 and ghrelin receptor binding and molecular function this GO :0032024 and positive regulation of insulin secretion and biological process this GO :0032095 and regulation of response to food and biological process this GO :0032097 and positive regulation of response to food and biological process this GO :0032100 and positive regulation of appetite and biological process this GO :0032691 and negative regulation of interleukin-1 beta production and biological process this GO :0034774 and secretory granule lumen and cellular component this GO :0040013 and negative regulation of locomotion and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042322 and negative regulation of circadian sleep/wake cycle, this GO :0001664 : G-protein coupled receptor binding, this GO :0001664 : G-protein coupled receptor binding and also this GO :0005179 : hormone activity and also this GO :0016608 : growth hormone-releasing hormone activity and also this GO :0030296 : protein tyrosine kinase activator activity and also this GO :0031768 : ghrelin receptor binding, this GO :0005179 : hormone activity, this GO :0016608 : growth hormone-releasing hormone activity, this GO :0030296 : protein tyrosine kinase activator activity, this GO :0031768 : ghrelin receptor binding, ghrelin/obestatin prepropeptide |
| Identity: |
18129 |
| Gene: |
GHRL |
More about : GHRL |
| Long gene name: |
ghrelin and obestatin prepropeptide |
| Synonyms gene name: |
ghrelin, growth hormone secretagogue receptor ligand ghrelin/obestatin prepropeptide |
| Synonyms: |
MTLRP ghrelin obestatin |
| Synonyms name: |
prepro-appetite regulatory hormone |
| Locus: |
3p25, 3 |
| Discovery year: |
2006-01-05 |
| GenBank acession: |
AF296558 |
| Entrez gene record: |
51738 |
| Pubmed identfication: |
10930375 10604470 16284174 |
| RefSeq identity: |
NM_016362 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000155360 |