| Also known as: |
HSPA5 / GRP78 / BIP |
| Other names: |
78 kDa glucose-regulated protein, 78 kDa glucose-regulated protein, 78kDa), BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, epididymis secretory sperm binding protein Li 89n, heat shock 70kDa protein 5 (glucose-regulated protein, immunoglobulin heavy chain-binding protein, 78 kDa glucose-regulated protein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
HSPA5 |
| Gene name synonims: |
BIP, GRP78 |
| Other gene names: |
BIP, BiP, GRP-78, GRP78, GRP78, HEL-S-89n, HSPA5, MIF2, HSPA5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
4000 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human HSPA5 |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 03% sodium azide, Ascitic fluid |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 4E3] (IgG1) HSPA5 / GRP78 / BIP |
| Short name: |
Mouse Monoclonal [clone 4E3] (IgG1) HSPA5 / GRP78 / BIP Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
78kDa) / GRP78 / BIP (Antibody to), sapiens heat shock 70kDa protein 5 (glucose-regulated protein, Mouse monoclonal [clonality 4E3] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
78kDa), BIP and GRP78 and HEL-S-89n and MIF2, HSPA5 and IDBG-85148 and ENSG00000044574 and 3309, Hspa5 and IDBG-163151 and ENSMUSG00000026864 and 14828, misfolded protein binding, nuclei, this GO :0000902 and cell morphogenesis and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005790 and smooth endoplasmic reticulum and cellular component this GO :0005793 and endoplasmic reticulum- this GO lgi intermediate compartment and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006983 and ER overload response and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0007596 and blood coagulation and biological process this GO :0008180 and COP9 signalosome and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021589 and cerebellum structural organization and biological process this GO :0021680 and cerebellar Purkinje cell layer development and biological process this GO :0021762 and substantia nigra development and biological process this GO :0030168 and platelet activation and biological process this GO :0030176 and integral component of endoplasmic reticulum membrane and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0030433 and ER-associated ubiquitin-dependent protein catabolic process and biological process this GO :0030496 and midbody and cellular component this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0034663 and endoplasmic reticulum chaperone complex and cellular component this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0035437 and maintenance of protein localization in endoplasmic reticulum and biological process this GO :0042149 and cellular response to glucose starvation and biological process this GO :0042470 and melanosome and cellular component this GO :0043022 and ribosome binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0051082 and unfolded protein binding and molecular function this GO :0051087 and chaperone binding and molecular function this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :0051787 and misfolded protein binding and molecular function this GO :0060904 and regulation of protein folding in endoplasmic reticulum and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071236 and cellular response to antibiotic and biological process this GO :0071353 and cellular response to interleukin-4 and biological process, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016887 : ATPase activity and also this GO :0019899 : enzyme binding and also this GO :0019904 : protein domain specific binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0043022 : ribosome binding and also this GO :0051082 : unfolded protein binding and also this GO :0051087 : chaperone binding and also this GO :0051787 : misfolded protein binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016887 : ATPase activity, this GO :0019899 : enzyme binding, this GO :0019904 : protein domain specific binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0043022 : ribosome binding, this GO :0051082 : unfolded protein binding, this GO :0051087 : chaperone binding, this GO :0051787 : misfolded protein binding, heat shock 70kDa protein 5 (glucose-regulated protein |
| Identity: |
5238 |
| Gene: |
HSPA5 |
More about : HSPA5 |
| Long gene name: |
heat shock protein family A (Hsp70) member 5 |
| Synonyms gene: |
GRP78 |
| Synonyms gene name: |
78kD) heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) , heat shock 70kD protein 5 (glucose-regulated protein |
| Synonyms: |
BiP |
| Synonyms name: |
78kDa , glucose-regulated protein |
| Locus: |
9q33, 3 |
| Discovery year: |
1991-07-26 |
| Entrez gene record: |
3309 |
| Classification: |
Heat shock 70kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000020672 |