| Also known as: |
WT1 / Wilms Tumor 1 |
| Other names: |
WT33, Wilms tumor 1, Wilms tumor protein, Wilms tumor protein, amino-terminal domain of EWS|last three zinc fingers of the DNA-binding domain of WT1, Wilms tumor protein isoform D |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
WT1 |
| Other gene names: |
AWT1, EWS-WT1, GUD, N/A, NPHS4, WAGR, WIT-2, WT1, WT33, WT1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
1000000000 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human WT1 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
4 mg/ml |
| Storage and shipping: |
Avoid repeat freeze-thaw cycles, For optimal long term storage, the antibody should be kept at -20 degrees Celsius, For long term |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 1E9] (IgG2a, k) WT1 / Wilms Tumor 1 |
| Short name: |
Mouse Monoclonal [clone 1E9] (IgG2a, k) WT1 / Wilms Tumor 1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens Wilms tumor 1 / Wilms Tumor 1 (Antibody to), Mouse monoclonal [clonality 1E9] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AWT1 and EWS-WT1 and GUD and NPHS4 and WAGR and WIT-2 and WT33, C2H2 zinc finger domain binding, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007281 and germ cell development and biological process this GO :0007356 and thorax and anterior abdomen determination and biological process this GO :0007507 and heart development and biological process this GO :0007530 and sex determination and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008380 and RNA splicing and biological process this GO :0008406 and this GO nad development and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009888 and tissue development and biological process this GO :0016607 and nuclear speck and cellular component this GO :0017148 and negative regulation of translation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030539 and male genitalia development and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0032835 and glomerulus development and biological process this GO :0032836 and glomerular basement membrane development and biological process this GO :0035802 and adrenal cortex formation and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0060231 and mesenchymal to epithelial transition and biological process this GO :0060421 and positive regulation of heart growth and biological process this GO :0060539 and diaphragm development and biological process this GO :0060923 and cardiac muscle cell fate commitment and biological process this GO :0061032 and visceral serous pericardium development and biological process this GO :0070742 and C2H2 zinc finger domain binding and molecular function this GO :0071320 and cellular response to cAMP and biological process this GO :0071371 and cellular response to this GO nadotropin stimulus and biological process this GO :0072075 and metanephric mesenchyme development and biological process this GO :0072112 and glomerular visceral epithelial cell differentiation and biological process this GO :0072166 and posterior mesonephric tubule development and biological process this GO :0072207 and metanephric epithelium development and biological process this GO :0072284 and metanephric S-shaped body morphogenesis and biological process this GO :0072302 and negative regulation of metanephric glomerular mesangial cell proliferation and biological process this GO :1900212 and negative regulation of mesenchymal cell apoptotic process involved in metanephros development and biological process this GO :2000020 and positive regulation of male this GO nad development and biological process this GO :2000195 and negative regulation of female this GO nad development and biological process this GO :2001076 and positive regulation of metanephric ureteric bud development and biological process, WT1 and IDBG-37982 and ENSG00000184937 and 7490, WT1 and IDBG-636230 and ENSBTAG00000047268 and 782183, Wt1 and IDBG-194872 and ENSMUSG00000016458 and 22431, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001570 and vasculogenesis and biological process this GO :0001656 and metanephros development and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001822 and kidney development and biological process this GO :0001823 and mesonephros development and biological process this GO :0003156 and regulation of organ formation and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003723 and RNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006351 and transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003676 : nucleic acid binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003723 : RNA binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046872 : metal ion binding and also this GO :0070742 : C2H2 zinc finger domain binding, this GO :0003676 : nucleic acid binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003723 : RNA binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046872 : metal ion binding, this GO :0070742 : C2H2 zinc finger domain binding, Wilms tumor 1 |
| Identity: |
12796 |
| Gene: |
WT1 |
More about : WT1 |
| Long gene name: |
Wilms tumor 1 |
| Synonyms gene: |
GUD |
| Synonyms: |
WAGR WIT-2 AWT1 NPHS4 |
| Locus: |
11p13 |
| Discovery year: |
1989-04-13 |
| Entrez gene record: |
7490 |
| Pubmed identfication: |
14681303 |
| RefSeq identity: |
NM_000378 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000039556 |
| Locus Specific Databases: |
LRG_525 |