WT1 Antibody (Wilms Tumor protein)

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Catalog number: F41819-0.08ML
Price: 199 €
Supplier: NJS poly
Product name: WT1 Antibody (Wilms Tumor protein)
Quantity: 0.08 ml
Other quantities: 0.4 ml 406€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: WT1 (Wilms Tumor protein)
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, IHC, WB, IF
Recommended dilutions: Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the WT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This WT1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P19544
Purity: Antigen affinity
Description: Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, In several variants, It has an essential role in the normal development of the urogenital system, Multiple transcript variants have been described, This gene exhibits complex tissue-specific and polymorphic imprinting pattern, [provided by RefSeq], and it is mutated in a small subset of patients with Wilm's tumors, and monoallelic expression from the maternal and paternal alleles in different tissues, and that this process is tissue-restricted and developmentally regulated, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG, with biallelic, Wilms Tumor protein is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus
Immunogen: A portion of amino acids 346-375 from the human protein was used as the immunogen for this WT1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the WT1 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: WT1 (Wilms Tumor protein)
Short name: WT1 Antibody (Wilms Tumor protein)
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: Wilms tumor 1 (Antibody to) (Wilms Tumor protein)
Alternative technique: antibodies
Alternative to gene target: AWT1 and EWS-WT1 and GUD and NPHS4 and WAGR and WIT-2 and WT33, C2H2 zinc finger domain binding, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007281 and germ cell development and biological process this GO :0007356 and thorax and anterior abdomen determination and biological process this GO :0007507 and heart development and biological process this GO :0007530 and sex determination and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008380 and RNA splicing and biological process this GO :0008406 and this GO nad development and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009888 and tissue development and biological process this GO :0016607 and nuclear speck and cellular component this GO :0017148 and negative regulation of translation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030539 and male genitalia development and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0032835 and glomerulus development and biological process this GO :0032836 and glomerular basement membrane development and biological process this GO :0035802 and adrenal cortex formation and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0060231 and mesenchymal to epithelial transition and biological process this GO :0060421 and positive regulation of heart growth and biological process this GO :0060539 and diaphragm development and biological process this GO :0060923 and cardiac muscle cell fate commitment and biological process this GO :0061032 and visceral serous pericardium development and biological process this GO :0070742 and C2H2 zinc finger domain binding and molecular function this GO :0071320 and cellular response to cAMP and biological process this GO :0071371 and cellular response to this GO nadotropin stimulus and biological process this GO :0072075 and metanephric mesenchyme development and biological process this GO :0072112 and glomerular visceral epithelial cell differentiation and biological process this GO :0072166 and posterior mesonephric tubule development and biological process this GO :0072207 and metanephric epithelium development and biological process this GO :0072284 and metanephric S-shaped body morphogenesis and biological process this GO :0072302 and negative regulation of metanephric glomerular mesangial cell proliferation and biological process this GO :1900212 and negative regulation of mesenchymal cell apoptotic process involved in metanephros development and biological process this GO :2000020 and positive regulation of male this GO nad development and biological process this GO :2000195 and negative regulation of female this GO nad development and biological process this GO :2001076 and positive regulation of metanephric ureteric bud development and biological process, WT1 and IDBG-37982 and ENSG00000184937 and 7490, WT1 and IDBG-636230 and ENSBTAG00000047268 and 782183, Wt1 and IDBG-194872 and ENSMUSG00000016458 and 22431, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001570 and vasculogenesis and biological process this GO :0001656 and metanephros development and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001822 and kidney development and biological process this GO :0001823 and mesonephros development and biological process this GO :0003156 and regulation of organ formation and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003723 and RNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006351 and transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003676 : nucleic acid binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003723 : RNA binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046872 : metal ion binding and also this GO :0070742 : C2H2 zinc finger domain binding, this GO :0003676 : nucleic acid binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003723 : RNA binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046872 : metal ion binding, this GO :0070742 : C2H2 zinc finger domain binding, Wilms tumor 1
Identity: 12796
Gene: WT1 | More about : WT1
Long gene name: Wilms tumor 1
Synonyms gene: GUD
Synonyms: WAGR WIT-2 AWT1 NPHS4
Locus: 11p13
Discovery year: 1989-04-13
Entrez gene record: 7490
Pubmed identfication: 14681303
RefSeq identity: NM_000378
Classification: Zinc fingers C2H2-type
Havana BLAST/BLAT: OTTHUMG00000039556
Locus Specific Databases: LRG_525

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