| Also known as: |
CFH / Complement Factor H |
| Other names: |
Complement factor H, H factor 1, H factor 1 (complement), H factor 2 (complement), adrenomedullin binding protein, age-related maculopathy susceptibility 1, beta-1-H-globulin, beta-1H, complement factor H, complement factor H, complement factor H, factor H-like 1, isoform b, complement factor H isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CFH |
| Other gene names: |
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, FH, FHL1, HF, HF, HF1, HF1, HF2, HF2, HUS, CFH |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
OX-24 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antibody recognizes the human serum complement protein factor H and a 43-49kD truncated form of factor H present at, This particular antibody might cross react with speacies outside of the listed ones, Purified anti-human factor H (beta 1H) (139 kD) monoclonal antibody clone OX-24 inhibits the binding of factor H to surface bound C3 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, Sourced in Ascites, 02% sodium azide, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage, aliquot and For optimal long term storage, for short term applications, the antibody should be kept at -20 degrees Celsius, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ OX-24] (IgG1) CFH / Complement Factor H |
| Short name: |
Mouse Monoclonal [clone OX-24] (IgG1) CFH / Complement Factor H Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens complement factor H / Complement Factor H (Antibody to), Mouse monoclonal [clonality OX-24] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AHUS1 and AMBP1 and ARMD4 and ARMS1 and CFHL3 and FH and FHL1 and HF and HF1 and HF2 and HUS, CFH and IDBG-105504 and ENSG00000000971 and 3075, Extracellular, alternative pathway and biological process this GO :0008201 and heparin binding and molecular function this GO :0030449 and regulation of complement activation and biological process this GO :0043395 and heparan sulfate proteoglycan binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0072562 and blood microparticle and cellular component, heparan sulfate proteoglycan binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0043395 : heparan sulfate proteoglycan binding, this GO :0008201 : heparin binding, this GO :0043395 : heparan sulfate proteoglycan binding, complement factor H |
| Identity: |
4883 |
| Gene: |
CFH |
More about : CFH |
| Long gene name: |
complement factor H |
| Synonyms gene: |
HF HF1 HF2 |
| Synonyms gene name: |
H factor 1 (complement) |
| Synonyms: |
HUS FHL1 ARMS1 ARMD4 |
| Synonyms name: |
beta-1H H factor 2 (complement) age-related maculopathy susceptibility 1 |
| Locus: |
1q31, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
Y00716 |
| Entrez gene record: |
3075 |
| Pubmed identfication: |
2889480 2963625 |
| RefSeq identity: |
NM_000186 |
| Classification: |
Sushi domain containing Complement system |
| Havana BLAST/BLAT: |
OTTHUMG00000035607 |
| Locus Specific Databases: |
CFHbase: Mutation registry for Factor H deficiency (previously known as HF1base) LRG_47 |