| Also known as: |
CFH / Complement Factor H |
| Other names: |
Complement factor H, H factor 1, H factor 1 (complement), H factor 2 (complement), adrenomedullin binding protein, age-related maculopathy susceptibility 1, beta-1-H-globulin, beta-1H, complement factor H, complement factor H, complement factor H, factor H-like 1, isoform b, complement factor H isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CFH |
| Other gene names: |
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, FH, FHL1, HF, HF, HF1, HF1, HF2, HF2, HUS, CFH |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
OX-24 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
In an immunoprecipitation system, Recognizes Factor H in Western blotting procedures, Recognizes factor H in other primates, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The Recognizes a 43-49kD truncated form of factor H present at low level (1-5 ug/ml) in plasma and urine, This antibody inhibits the binding of factor H to surface bound C3b, This particular antibody might cross react with speacies outside of the listed ones, binding to a different epitope from MRC OX23, but not in cow, chicken or rabbit sera, pig, sheep, Recognizes the human serum complement protein factor H (155kD) |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
09% sodium azide |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ OX-24] (IgG1) CFH / Complement Factor H |
| Short name: |
Mouse Monoclonal [clone OX-24] (IgG1) CFH / Complement Factor H Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens complement factor H / Complement Factor H (Antibody to), Mouse monoclonal [clonality OX-24] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AHUS1 and AMBP1 and ARMD4 and ARMS1 and CFHL3 and FH and FHL1 and HF and HF1 and HF2 and HUS, CFH and IDBG-105504 and ENSG00000000971 and 3075, Extracellular, alternative pathway and biological process this GO :0008201 and heparin binding and molecular function this GO :0030449 and regulation of complement activation and biological process this GO :0043395 and heparan sulfate proteoglycan binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0072562 and blood microparticle and cellular component, heparan sulfate proteoglycan binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0043395 : heparan sulfate proteoglycan binding, this GO :0008201 : heparin binding, this GO :0043395 : heparan sulfate proteoglycan binding, complement factor H |
| Identity: |
4883 |
| Gene: |
CFH |
More about : CFH |
| Long gene name: |
complement factor H |
| Synonyms gene: |
HF HF1 HF2 |
| Synonyms gene name: |
H factor 1 (complement) |
| Synonyms: |
HUS FHL1 ARMS1 ARMD4 |
| Synonyms name: |
beta-1H H factor 2 (complement) age-related maculopathy susceptibility 1 |
| Locus: |
1q31, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
Y00716 |
| Entrez gene record: |
3075 |
| Pubmed identfication: |
2889480 2963625 |
| RefSeq identity: |
NM_000186 |
| Classification: |
Sushi domain containing Complement system |
| Havana BLAST/BLAT: |
OTTHUMG00000035607 |
| Locus Specific Databases: |
CFHbase: Mutation registry for Factor H deficiency (previously known as HF1base) LRG_47 |