| Also known as: |
HIF2 ALPHA |
| Other names: |
Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, EPAS-1, Endothelial PAS domain-containing protein 1, HIF-1-alpha-like factor, HIF-1-alpha-like factor, HIF-1alpha-like factor, HIF-2-alpha, HIF-2-alpha, HIF2-alpha, HIF2-alpha, HLF, Hypoxia-inducible factor 2-alpha, Member of PAS protein 2, PAS domain-containing protein 2, PAS domain-containing protein 2, bHLHe73, basic-helix-loop-helix-PAS protein MOP2, class E basic helix-loop-helix protein 73, endothelial PAS domain protein 1, endothelial PAS domain-containing protein 1, hypoxia-inducible factor 2 alpha, hypoxia-inducible factor 2-alpha, member of PAS protein 2, endothelial PAS domain-containing protein 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
HIF2 ALPHA |
| Other gene names: |
BHLHE73, ECYT4, EPAS-1, EPAS1, HIF-2-alpha, HIF2-alpha, HIF2A, HIF2A, HLF, HLF, MOP2, MOP2, PASD2, PASD2, bHLHe73, bHLHe73, EPAS1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
Hif2alpha237 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Mutations in HIF2A are responsible for the autosomal dominant disorder erythrocytosis familial type 4 (ECYT4), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D_HIF2A is involved in the regulation of vascular endothelial growth factor (VEGF) expression, a nuclear transcription factor, and haematocrit, and is implicated in vasculogenesis, characterized by elevated haemoglobin concentration, during oxygen depravation (hypoxia), increased serum red blood cell mass, otherwise known as EPAS-1 (endothelial PAS domain-containing protein 1), selectively expressed by endothelial cells, which acts as an inducer of oxygen-regulated genes, HIF2 ALPHA This item specifically recognizes human HIF2 alpha (HIF2A) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from the date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
HIF2 ALPHA |
| Short name: |
MOUSE Anti-HUMAN HIF2 ALPHA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens HIF2 a (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |