| Long name: |
ALEXA FLUOR 488 Conjugated, HIF2 alpha Polyclonal Antibody |
| Also known as: |
Anti-HIF2 alpha PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HIF2 alpha |
| Specificity: |
This is a highly specific antibody against HIF2 alpha |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/874 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from mouse HIF2 Alpha |
| Gene ID Number: |
13819 |
| Swiss Prot: |
P97481 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP3, Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters, Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity), May also play a role in the formation of the endothelium that gives rise to the blood brain barrier, Potent activator of the Tie-2 tyrosine kinase expression, Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung, Transcription factor involved in the induction of oxygen regulated genes |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
EPAS-1, Endothelial PAS domain-containing protein 1, Epas1, HIF-1-alpha-like factor, HIF-2-alpha, HIF-2alpha, HIF-related factor, HIF2-alpha, HIF2A, HRF, Hypoxia-inducible factor 2-alpha, MOP2, bHLHe73, mHLF, HLF |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the HIF2 alpha Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
HIF2 alpha |
| Short name: |
HIF2 alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, HIF2 a (Antibody to) |
| Alternative technique: |
antibodies |