| Also known as: |
CD49f |
| Other names: |
CD49 antigen-like family member F, CD49 antigen-like family member F, Integrin alpha-6, VLA-6, alpha 6, integrin, integrin alpha-6, integrin alpha6B, integrin alpha-6 isoform b |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD49f |
| Other gene names: |
CD49f, ITGA6, ITGA6B, N/A, VLA-6, ITGA6 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
NKI-GoH3 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Clone NKI-GoH3 reacts with platelets, In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies suggest that clone NKI-GoH3 specifically blocks the binding of cells to the E8 fragment of laminin, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1), This particular antibody might cross react with speacies outside of the listed ones, a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), megakaryocytes, microvascular endothelial cells, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells, peripheral nerves, placenta cyto- and syncytotrophoblasts, resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, CD49f This item recognises CD49F (VLA-6 alpha chain), VLA-6 is an important mediator of cell binding to laminin |
| Form/Appearance: |
Low Endotoxin (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, the antibody should be stored undiluted, Store at -20 degree only |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Functional Assay (FA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD49f: Endotoxin |
| Short name: |
RAT ANTI HUMAN CD49f:Low Endotoxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD49f:Low Endotoxin (Antibody to), RAT antibody to H |
| Alternative technique: |
antibodies |