| Also known as: |
CD71 |
| Other names: |
N/A, TR, Transferrin receptor protein 1, tfR, tfR1, transferrin receptor, transferrin receptor protein 1, Transferrin receptor protein 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD71 |
| Other gene names: |
TR, TfR, TfR1, Tfrc, Trfr, Trfr, Trfr, Tfrc |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
OX-26 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus) |
| Specificity and cross-reactivity: |
(Mwt 195kDa without reduction), Alzheimer's, An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Clone MRC OX-26 is reported as suitable for use in Electron Microscopy This item detects a band of approximately 95kDa in ConA cell lysates under reducing conditions in Western blotting, Huntington's and Multiple Sclerosis, Parkinson's, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The balance between a sufficient amount of iron uptake and prevention of accumulation of excess iron within a cell, This item also binds to a number of non-dividing normal tissues, This particular antibody might cross react with speacies outside of the listed ones, Transferrin receptor (CD71), a homodimeric type II transmembrane protein, also known as transferrin receptor, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain, is vitally important to maintain cellular functions such as oxygen and electron transport and mitochondrial energy metabolism, thereby maintaining iron homeostasis, transferrin and ferritin have been identified as specialised proteins which control the uptake, transport and storage of free iron in tissues, whilst preventing permanent cell and tissue damage, CD71 This item recognises rat CD71 |
| Form/Appearance: |
Low Endotoxin (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, only, the antibody should be stored undiluted, Store the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistology - Frozen (IHC), Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD71: Endotoxin |
| Short name: |
MOUSE Anti-RAT CD71:Low Endotoxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-RAT CD71:Low Endotoxin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11763 |
| Gene: |
TFRC |
More about : TFRC |
| Long gene name: |
transferrin receptor |
| Synonyms gene name: |
CD71) , transferrin receptor (p90 |
| Synonyms: |
CD71 TFR1 p90 |
| Locus: |
3q29 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X01060 |
| Entrez gene record: |
7037 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000155714 |