| Also known as: |
CD49d |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD49d |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
MRalpha4-1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus) |
| Specificity and cross-reactivity: |
CD49d is expressed broadly on T and B lymphocytes, Clone MRalpha4-1 inhibits the <, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 150kDa type-1 transmembrane glycoprotein and member of the integrin alpha chain family, and <, and significantly inhibits the transendothelial migration of T lymphocytes, and the adhesion of cells to the extracellular matrix, clone MRalpha4-1 inhibits the rolling and adherence of lymphocytes to postcapillary venules (PCV), functions of CD49d Studies have shown that in rat Peyer's patches, mast cells and dendritic cells and is involved in cell-cell interactions, monocytes, mononuclear cell trafficking to sites of endothelial inflammation, otherwise known as integrin alpha 4 chain/VLA-4, thymocytes, which acts as a receptor for fibronectin and CD106 (VCAM-1), /i>, /i>, CD49d This item specifically recognises rat CD49d, i>, i>, in vitro<, in vivo< |
| Form/Appearance: |
Low Endotoxin (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, only, the antibody should be stored undiluted, Store the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
Functional Assay (FA), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD49d: Endotoxin |
| Short name: |
MOUSE Anti-RAT CD49d:Low Endotoxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-RAT CD49d:Low Endotoxin (Antibody to) |
| Alternative technique: |
antibodies |