| known also as: |
Anti-Goat Polyclonal to Human AIRE |
| known also as: |
Caprine PAb to Human AIRE |
| known also as: |
Caprinae Polyclonal to Homo sapiens AIRE |
| known also as: |
AIRE |
| known also as: |
AIRE, AIRE1, APECED, APECED protein, APS1, APSI, Autoimmune regulator, Human AIRE, PGA1, Anti-AIRE Antibody (Internal) IHC-plus |
| Other names: |
APECED protein, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, autoimmune regulator, autoimmune regulator, autoimmune regulator |
| Gene name: |
AIRE |
| Other gene names: |
AIRE, AIRE1, APECED, APECED, APECED protein, APS1, APSI, PGA1, AIRE |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Gorilla, Hamster, Horse, Human, Rat, Dog |
| Specificity and cross-reactivity: |
This antibody is expected to recognise isoform 1 (NP_000374, 1) only, Human AIRE |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Tris-buffered saline |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Minimize freezing and thawing, productone should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| Latin name: |
Capra aegagrus hircus |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AIRE |
| Short name: |
Goat Polyclonal AIRE Antibody |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , goats, whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
It are very good secondary antibodies that are affinity purified and have a good affinity themselves too, Often KLH is coupled to the antigen so anti KLH can be present in the vial, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection, Goat |
| Species: |
Goats, Humans, Human |
| Alternative name: |
sapiens autoimmune regulator (Antibody to), caprine polyclonal to H |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AIRE and IDBG-5152 and ENSG00000160224 and 326, AIRE and IDBG-639674 and ENSBTAG00000023393 and, AIRE1 and APECED and APS1 and APSI and PGA1, Aire and IDBG-168233 and ENSMUSG00000000731 and 11634, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006417 and regulation of translation and biological process this GO :0006955 and immune response and biological process this GO :0006959 and humoral immune response and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0042393 and histone binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045182 and translation regulator activity and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0042393 : histone binding and also this GO :0042802 : identical protein binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0045182 : translation regulator activity, this GO :0003682 : chromatin binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0042393 : histone binding, this GO :0042802 : identical protein binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0045182 : translation regulator activity, translation regulator activity, autoimmune regulator |
| Identity: |
360 |
| Gene: |
AIRE |
More about : AIRE |
| Long gene name: |
autoimmune regulator |
| Synonyms gene: |
APECED |
| Synonyms gene name: |
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) |
| Synonyms: |
PGA1 APS1 |
| Synonyms name: |
autoimmune polyendocrinopathy candidiasis ectodermal dystrophy |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
AB006684 |
| Entrez gene record: |
326 |
| Pubmed identfication: |
9398840 |
| Classification: |
PHD finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000086921 |
| Locus Specific Databases: |
AIREbase: Mutation registry for APECED LRG_18 |