| Long name: |
Recombinant Human Autoimmune regulator (AIRE) |
| Alternative names: |
APECED protein, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, autoimmune regulator, autoimmune regulator, autoimmune regulator |
| Gene name: |
AIRE |
| Other gene names: |
AIRE, AIRE1, APECED, APECED, APECED protein, APS1, APSI, PGA1, AIRE |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Autoimmune regulator (AIRE) is a recombinant protein expressed in Mammalian Cell |
| Product category: |
Recombinant Proteins |
| Expression system: |
Mammalian Cell |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Autoimmune regulator (AIRE) |
| Short name: |
Autoimmune regulator (AIRE) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Autoimmune regulator (autoimmune regulator), H |
| Alternative technique: |
immuno |
| Alternative to gene target: |
AIRE and IDBG-5152 and ENSG00000160224 and 326, AIRE and IDBG-639674 and ENSBTAG00000023393 and, AIRE1 and APECED and APS1 and APSI and PGA1, Aire and IDBG-168233 and ENSMUSG00000000731 and 11634, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006417 and regulation of translation and biological process this GO :0006955 and immune response and biological process this GO :0006959 and humoral immune response and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0042393 and histone binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045182 and translation regulator activity and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0042393 : histone binding and also this GO :0042802 : identical protein binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0045182 : translation regulator activity, this GO :0003682 : chromatin binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0042393 : histone binding, this GO :0042802 : identical protein binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0045182 : translation regulator activity, translation regulator activity, autoimmune regulator |
| Identity: |
360 |
| Gene: |
AIRE |
More about : AIRE |
| Long gene name: |
autoimmune regulator |
| Synonyms gene: |
APECED |
| Synonyms gene name: |
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) |
| Synonyms: |
PGA1 APS1 |
| Synonyms name: |
autoimmune polyendocrinopathy candidiasis ectodermal dystrophy |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
AB006684 |
| Entrez gene record: |
326 |
| Pubmed identfication: |
9398840 |
| Classification: |
PHD finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000086921 |
| Locus Specific Databases: |
AIREbase: Mutation registry for APECED LRG_18 |