| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AIRE |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB |
| Recommended dilutions: |
3-1ug/ml, ELISA (peptide) LOD: 1:64000, Western blot: 0 |
| Notes: |
Optimal dilution of the AIRE antibody should be determined by the researcher |
| Intented use: |
This AIRE antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
326 |
| Uniprot #: |
O43918 |
| Purity: |
Antigen affinity |
| Description: |
Additional name(s) for this target protein: Autoimmune regulator protein |
| Immunogen: |
(1), Amino acids KAKPPKKPESSAEQ were used as the immunogen for this AIRE antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the AIRE antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AIRE |
| Short name: |
AIRE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
autoimmune regulator (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AIRE and IDBG-5152 and ENSG00000160224 and 326, AIRE and IDBG-639674 and ENSBTAG00000023393 and, AIRE1 and APECED and APS1 and APSI and PGA1, Aire and IDBG-168233 and ENSMUSG00000000731 and 11634, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006417 and regulation of translation and biological process this GO :0006955 and immune response and biological process this GO :0006959 and humoral immune response and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0042393 and histone binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045182 and translation regulator activity and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0042393 : histone binding and also this GO :0042802 : identical protein binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0045182 : translation regulator activity, this GO :0003682 : chromatin binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0042393 : histone binding, this GO :0042802 : identical protein binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0045182 : translation regulator activity, translation regulator activity, autoimmune regulator |
| Identity: |
360 |
| Gene: |
AIRE |
More about : AIRE |
| Long gene name: |
autoimmune regulator |
| Synonyms gene: |
APECED |
| Synonyms gene name: |
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) |
| Synonyms: |
PGA1 APS1 |
| Synonyms name: |
autoimmune polyendocrinopathy candidiasis ectodermal dystrophy |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
AB006684 |
| Entrez gene record: |
326 |
| Pubmed identfication: |
9398840 |
| Classification: |
PHD finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000086921 |
| Locus Specific Databases: |
AIREbase: Mutation registry for APECED LRG_18 |