| Also known as: |
CD262 |
| Other names: |
Death receptor 5, Fas-like protein, TNF-related apoptosis-inducing ligand receptor 2, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B, apoptosis inducing protein TRICK2A/2B, apoptosis inducing receptor TRAIL-R2, cytotoxic TRAIL receptor-2, death domain containing receptor for TRAIL/Apo-2L, death receptor 5, member 10b, p53-regulated DNA damage-inducible cell death receptor(killer), tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor-like protein ZTNFR9, tumor necrosis factor receptor superfamily member 10B isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD262 |
| Other gene names: |
CD262, DR5, DR5, KILLER, KILLER, KILLER/DR5, TNFRSF10B, TRAIL receptor 2, TRAIL-R2, TRAIL-R2, TRAILR2, TRAILR2, TRICK2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, ZTNFR9, TNFRSF10B |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
DJR2-4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
DR5 is widely expressed in adult and fetal tissues, FADD, It is a 55kDa member of the TNF receptor superfamily binding tumor necrosis factor-related apoptosis inducing ligand (TNFSF10, Once activated, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Staining may be enhanced with the use of a sensitive, TRAIL or APO-2L), This particular antibody might cross react with speacies outside of the listed ones, a death domain containing adaptor protein is required for apoptosis mediated by DR5, also known as Death receptor 5 (DR5) and TNF-related apoptosis-inducing ligand receptor 2 (TRAIL-R2), this receptor induces a cascade of caspases resulting in apoptosis, three-layer staining technique, CD262 This item recognises human CD262 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD262 |
| Short name: |
MOUSE Anti-HUMAN CD262 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD262 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11905 |
| Gene: |
TNFRSF10B |
More about : TNFRSF10B |
| Long gene name: |
TNF receptor superfamily member 10b |
| Synonyms gene name: |
member 10b , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR5 KILLER TRICK2A TRAIL-R2 TRICKB CD262 |
| Locus: |
8p21, 3 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF012628 |
| Entrez gene record: |
8795 |
| Pubmed identfication: |
9285725 9311998 |
| RefSeq identity: |
NM_147187 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000097826 |