| known also as: |
Anti-GOAT ANTI HUMAN CD262 |
| known also as: |
Caprine ANTI HUMAN CD262 |
| known also as: |
Caprinae ANTI Homo sapiens CD262 |
| known also as: |
CD262 |
| Other names: |
Death receptor 5, Fas-like protein, TNF-related apoptosis-inducing ligand receptor 2, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B, apoptosis inducing protein TRICK2A/2B, apoptosis inducing receptor TRAIL-R2, cytotoxic TRAIL receptor-2, death domain containing receptor for TRAIL/Apo-2L, death receptor 5, member 10b, p53-regulated DNA damage-inducible cell death receptor(killer), tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor-like protein ZTNFR9, tumor necrosis factor receptor superfamily member 10B isoform 1 |
| Gene name: |
CD262 |
| Other gene names: |
CD262, DR5, DR5, KILLER, KILLER, KILLER/DR5, TNFRSF10B, TRAIL receptor 2, TRAIL-R2, TRAIL-R2, TRAILR2, TRAILR2, TRICK2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, ZTNFR9, TNFRSF10B |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Expression of CD262 is regulated by tumor suppressor p53, Studies suggest that the death domain containing adaptor protein FADD, This item is reported as suitable for use in immunocytochemistry, a broadly expressed death domain containing receptor and member of the TNF-receptor superfamily, and CD262 is highly expressed by tumour cell lines, and that FADD recruits caspase-8 to the activated receptor, but not in normal cells, is required for CD262-mediated apoptosis, otherwise known as DR5/TRAIL-R2, which acts as a mediator for CD253/TRAIL induced apoptosis in a variety of tumor and transformed cells, CD262 This item recognises CD262 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, only, productone should be stored undiluted, Store productone should be stored at -20 degrees Celsius |
| Tested for:: |
Flow Cytometry (FACS), Immunohistology - Paraffin (IHC), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CD262 |
| Short name: |
GOAT ANTI HUMAN CD262 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD262 (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
11905 |
| Gene: |
TNFRSF10B |
More about : TNFRSF10B |
| Long gene name: |
TNF receptor superfamily member 10b |
| Synonyms gene name: |
member 10b , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR5 KILLER TRICK2A TRAIL-R2 TRICKB CD262 |
| Locus: |
8p21, 3 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF012628 |
| Entrez gene record: |
8795 |
| Pubmed identfication: |
9285725 9311998 |
| RefSeq identity: |
NM_147187 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000097826 |