| Also known as: |
CD169 |
| Other names: |
SER, SER, Sheep erythrocyte receptor, Sialic acid-binding Ig-like lectin 1, Sialoadhesin, sheep erythrocyte receptor, sialic acid binding Ig-like lectin 1, sialic acid-binding Ig-like lectin 1, sialoadhesin, sialoadhesin, sialoadhesin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD169 |
| Other gene names: |
Cd169, SER, Sa, Siglec-1, Siglec-1, Siglec1, Sn, Sn, Siglec1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
MOMA-1 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Distinct macrophage subpopulations of lymphoid organs express the antigen, In Peyer's patches they are localised in the interfollicular areas at the serosal side, In lymph nodes, In non-lymphoid organs, In the spleen, Kupffer cells in the liver can be clearly stained by MOMA-1, No MOMA-1 positive macrophages were found in the thymus, No reactivity is seen with dendritic cells, Reactivity was also negative in following organs tested so far (kidney, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This item reacts with a subpopulation of mature resident tissue macrophages, This particular antibody might cross react with speacies outside of the listed ones, also known as sialoadhesin, although antigen expression is weaker than that seen in splenic macrophages, brain, peritoneal exudate cells or blood cells, peritoneal resident macrophages, skin), the antigen is only found on a macrophage subpopulation in the lamina propria of the villi of the small intestine, they are localised at the marginal sinus forming a ring around the periarteriolar lymphocyte sheath and follicular areas at the inner side of marginal zones, they are localised in the sinusoids and medullary cords but not within follicular areas or paracortex, CD169 This item is specific for CD169 |
| Form/Appearance: |
S/N (Tissue Culture Supernatant - liquid) |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology - Frozen (IHC), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD169 |
| Short name: |
RAT ANTI MOUSE CD169 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD169 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11127 |
| Gene: |
SIGLEC1 |
More about : SIGLEC1 |
| Long gene name: |
sialic acid binding Ig like lectin 1 |
| Synonyms gene: |
SN |
| Synonyms gene name: |
sialoadhesin , sialoadhesin sialic acid binding Ig-like lectin 1 |
| Synonyms: |
SIGLEC-1 CD169 FLJ00051 FLJ00055 FLJ00073 FLJ32150 dJ1009E24, 1 sialoadhesin |
| Locus: |
20p13 |
| Discovery year: |
1995-03-15 |
| GenBank acession: |
AF230073 |
| Entrez gene record: |
6614 |
| Pubmed identfication: |
8530048 |
| RefSeq identity: |
NM_023068 |
| Classification: |
C2-set domain containing I-set domain containing CD molecules Sialic acid binding Ig like lectins V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031757 |