| Also known as: |
CD169 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD169 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
ED3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus) |
| Specificity and cross-reactivity: |
CD169 is a receptor for glycoconjugates containing sialic acid, Furthermore, In healthy tissue no expression occurs, Monocytes and granulocytes are negative, No other cell types are positive, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly, This particular antibody might cross react with speacies outside of the listed ones, a 185kD molecule expressed by macrophages, macrophages in (auto-immune) diseased tissues express the ED3 antigen, predominately confined to lymphoid organs only, CD169 This item recognises the rat CD169 cell surface antigen |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD169 |
| Short name: |
MOUSE Anti-RAT CD169 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-RAT CD169 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11127 |
| Gene: |
SIGLEC1 |
More about : SIGLEC1 |
| Long gene name: |
sialic acid binding Ig like lectin 1 |
| Synonyms gene: |
SN |
| Synonyms gene name: |
sialoadhesin , sialoadhesin sialic acid binding Ig-like lectin 1 |
| Synonyms: |
SIGLEC-1 CD169 FLJ00051 FLJ00055 FLJ00073 FLJ32150 dJ1009E24, 1 sialoadhesin |
| Locus: |
20p13 |
| Discovery year: |
1995-03-15 |
| GenBank acession: |
AF230073 |
| Entrez gene record: |
6614 |
| Pubmed identfication: |
8530048 |
| RefSeq identity: |
NM_023068 |
| Classification: |
C2-set domain containing I-set domain containing CD molecules Sialic acid binding Ig like lectins V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031757 |