| Long name: |
FITC Conjugated, human Fibrinogen (4F7) Monoclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Mouse (Mus musculus) |
| Target Antigen: |
human Fibrinogen |
| Specificity: |
This is a highly specific antibody against human Fibrinogen |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Monoclonal |
| Clone: |
4F7 |
| Concentration: |
1ug per 1ul |
| Source: |
Fibrinogen from human plasma |
| Gene ID number: |
2243 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All chains are connected with each other by a number of disulfide bonds, All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases, An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A, Fibrinogen activation is also involved in pathogenesis of inflammation, Fibrinogen clotting underlies pathogenesis of MI, Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, In this way fibrinogen is converted into fibrin, It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases, The normal fibrinogen concentration in plasma is about 3 mg/ml, and Rapold H, beta and gamma, et al, et al), respectively, since fibrin is the main substrate for thrombus formation, thromboembolism and thromboses of arteries and veins, tumor growth and many other diseases, which by means of polymerization forms a fibrin clot, Fibrinogen is the main protein of blood coagulation system, J |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FGA protein, FGB, FGG, FIBA_HUMAN, Fib2, Fibrin alpha chain , Fibrinogen A alpha polypeptide chain, Fibrinogen B alpha polypeptide, Fibrinogen G alpha polypeptide, Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, MGC104327, MGC119422, MGC119423, MGC119425, MGC120405, FGA, Fibrinogen A alpha polypeptide |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Fibrinogen (4F7) Conjugated |
| Short name: |
FITC Conjugated, human Fibrinogen (4F7) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, sapiens Fibrinogen (4F7) (Antibody to), H |
| Alternative technique: |
antibodies |